Phenotype Images associated with this Gene

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Phenotype Images associated with this Gene

Symbol
Name
ID

Brca2
breast cancer 2, early onset
MGI:109337

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	Caption: Prostate hyperplasia and low-grade prostate intraepithelial neoplasia in Brca2^tm1Brn/Brca2^tm1Brn Tg(Pbsn-cre)4Prb/0 mice (details) Represented Alleles: Brca2^tm1Brn, breast cancer 2, early onset; targeted mutation 1, Anton Berns Tg(Pbsn-cre)4Prb, transgene insertion 4, Pradip Roy-Burman Copyright: This image is from Francis JC, PLoS Genet 2010;6(6):e1000995, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:161511
	Caption: High-grade prostate intraepithelial neoplasia in Brca2^tm1Brn/Brca2^tm1Brn Tg(Pbsn-cre)4Prb/0 Trp53^tm1Brn/Trp53^tm1Brn and prostate hyperplasia and intraepithelial neoplasia in Brca2^tm1Brn/Brca2^tm1Brn Trp53^tm1Brn/Trp53⁺ Tg(Pbsn-cre)4Prb/0 mice (details) Represented Alleles: Brca2^tm1Brn, breast cancer 2, early onset; targeted mutation 1, Anton Berns Tg(Pbsn-cre)4Prb, transgene insertion 4, Pradip Roy-Burman Trp53^tm1Brn, transformation related protein 53; targeted mutation 1, Anton Berns Copyright: This image is from Francis JC, PLoS Genet 2010;6(6):e1000995, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:161511
	Caption: Increased DNA damage and apoptosis in prostates of various prostate-specific conditional Brca2^tm1Brn and double Brca2^tm1Brn and Trp53^tm1Brn mutants (details) Represented Alleles: Brca2^tm1Brn, breast cancer 2, early onset; targeted mutation 1, Anton Berns Tg(Pbsn-cre)4Prb, transgene insertion 4, Pradip Roy-Burman Trp53^tm1Brn, transformation related protein 53; targeted mutation 1, Anton Berns Copyright: This image is from Francis JC, PLoS Genet 2010;6(6):e1000995, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:161511
	Caption: Brca2^tm1Brn/Brca2^tm1Brn Trp53^tm1Brn/Trp53^tm1Brn Tg(Pbsn-cre)4Prb/0 prostates have hallmarks of cancer (details) Represented Alleles: Brca2^tm1Brn, breast cancer 2, early onset; targeted mutation 1, Anton Berns Tg(Pbsn-cre)4Prb, transgene insertion 4, Pradip Roy-Burman Trp53^tm1Brn, transformation related protein 53; targeted mutation 1, Anton Berns Copyright: This image is from Francis JC, PLoS Genet 2010;6(6):e1000995, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:161511
	Caption: Brca2^tm1Brn/Brca2^tm1Brn Trp53^tm1Brn/Trp53^tm1Brn Tg(Pbsn-cre)4Prb/0 prostate intraepithelial neoplasia lesions proliferate post-castration (details) Represented Alleles: Brca2^tm1Brn, breast cancer 2, early onset; targeted mutation 1, Anton Berns Tg(Pbsn-cre)4Prb, transgene insertion 4, Pradip Roy-Burman Trp53^tm1Brn, transformation related protein 53; targeted mutation 1, Anton Berns Copyright: This image is from Francis JC, PLoS Genet 2010;6(6):e1000995, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:161511

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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