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Symbol Name ID |
Pten
phosphatase and tensin homolog MGI:109583 |
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Caption: Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl Ptentm1Hwu/Ptentm1Hwu Tg(KRT14-cre/ERT)20Efu/0 mice develop anal squamous cell carcinoma
(details)
Represented Alleles:
Ptentm1Hwu,
phosphatase and tensin homolog; targeted mutation 1, Hong Wu
Tgfbr1tm1.1Karl,
transforming growth factor, beta receptor I; targeted mutation 1.1, Stefan Karlsson
Copyright: This image is from Sun ZJ, PLoS One 2013;8(10):e74888, and is displayed under the terms of the Creative Commons Attribution 4.0 International License.
J:209026
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Caption: Increase in mesenchymal cell proliferation in Ptentm1Hwu/Ptentm1Hwu Twist2tm1.1(cre)Dor/Twist2+ mice
(details)
Represented Alleles:
Ptentm1Hwu,
phosphatase and tensin homolog; targeted mutation 1, Hong Wu
Twist2tm1.1(cre)Dor,
twist basic helix-loop-helix transcription factor 2; targeted mutation 1.1, David M Ornitz
Copyright: This image is from Tiozzo C, J Clin Invest 2012 Nov 1;122(11):3862-72 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright.
J:192736
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Caption: Abnormal airway capillary coupling in Ptentm1Hwu/Ptentm1Hwu Twist2tm1.1(cre)Dor/Twist2+ mice
(details)
Represented Alleles:
Ptentm1Hwu,
phosphatase and tensin homolog; targeted mutation 1, Hong Wu
Twist2tm1.1(cre)Dor,
twist basic helix-loop-helix transcription factor 2; targeted mutation 1.1, David M Ornitz
Copyright: This image is from Tiozzo C, J Clin Invest 2012 Nov 1;122(11):3862-72 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright.
J:192736
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Caption: Defect in angioblast differentiation in Ptentm1Hwu/Ptentm1Hwu Kdrtm1Jrt/Kdr+ Twist2tm1.1(cre)Dor/Twist2+ mice
(details)
Represented Alleles:
Kdrtm1Jrt,
kinase insert domain protein receptor; targeted mutation 1, Janet Rossant
Ptentm1Hwu,
phosphatase and tensin homolog; targeted mutation 1, Hong Wu
Twist2tm1.1(cre)Dor,
twist basic helix-loop-helix transcription factor 2; targeted mutation 1.1, David M Ornitz
Copyright: This image is from Tiozzo C, J Clin Invest 2012 Nov 1;122(11):3862-72 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright.
J:192736
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Caption: Vascular defects in Ptentm1Hwu/Ptentm1Hwu Twist2tm1.1(cre)Dor/Twist2+ embryos
(details)
Represented Alleles:
Ptentm1Hwu,
phosphatase and tensin homolog; targeted mutation 1, Hong Wu
Twist2tm1.1(cre)Dor,
twist basic helix-loop-helix transcription factor 2; targeted mutation 1.1, David M Ornitz
Copyright: This image is from Tiozzo C, J Clin Invest 2012 Nov 1;122(11):3862-72 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright.
J:192736
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Caption: Generalized lack of vascularization in Ptentm1Hwu/Ptentm1Hwu Twist2tm1.1(cre)Dor/Twist2+ mice
(details)
Represented Alleles:
Ptentm1Hwu,
phosphatase and tensin homolog; targeted mutation 1, Hong Wu
Twist2tm1.1(cre)Dor,
twist basic helix-loop-helix transcription factor 2; targeted mutation 1.1, David M Ornitz
Copyright: This image is from Tiozzo C, J Clin Invest 2012 Nov 1;122(11):3862-72 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright.
J:192736
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Caption: Prostate cancer progression in Tg(Pbsn-cre)4Prb/0 Gt(ROSA)26Sortm1(CAG-Bmi1,-EGFP)Nki/Gt(ROSA)26Sor+, Tg(Pbsn-cre)4Prb/0 Ptentm1Mro/Pten+, and Tg(Pbsn-cre)4Prb/0 Gt(ROSA)26Sortm1(CAG-Bmi1,-EGFP)Nki/Gt(ROSA)26Sor+ Ptentm1Mro/Pten+ mice
(details)
Represented Alleles:
Gt(ROSA)26Sortm1(CAG-Bmi1,-EGFP)Nki,
gene trap ROSA 26, Philippe Soriano; targeted mutation 1, The Netherlands Cancer Institute
Ptentm1Mro,
phosphatase and tensin homolog; targeted mutation 1, Silvia Marino
Tg(Pbsn-cre)4Prb,
transgene insertion 4, Pradip Roy-Burman
Copyright: This image is from Nacerddine K, J Clin Invest 2012 May 1;122(5):1920-32 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright.
J:184533
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Caption: Prostate lesions in Tg(Pbsn-cre)4Prb/0 Gt(ROSA)26Sortm1(CAG-Bmi1,-EGFP)Nki/Gt(ROSA)26Sor+, Tg(Pbsn-cre)4Prb/0 Ptentm1Mro/Pten+, and Tg(Pbsn-cre)4Prb/0 Gt(ROSA)26Sortm1(CAG-Bmi1,-EGFP)Nki/Gt(ROSA)26Sor+ Ptentm1Mro/Pten+ mice
(details)
Represented Alleles:
Gt(ROSA)26Sortm1(CAG-Bmi1,-EGFP)Nki,
gene trap ROSA 26, Philippe Soriano; targeted mutation 1, The Netherlands Cancer Institute
Ptentm1Mro,
phosphatase and tensin homolog; targeted mutation 1, Silvia Marino
Tg(Pbsn-cre)4Prb,
transgene insertion 4, Pradip Roy-Burman
Copyright: This image is from Nacerddine K, J Clin Invest 2012 May 1;122(5):1920-32 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright.
J:184533
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Caption: Ovary tumors in Pik3catm1.1Waph/Pik3catm1.1Waph Ptentm1Hwu/Ptentm1Hwu mice
(details)
Represented Alleles:
Pik3catm1.1Waph,
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; targeted mutation 1.1, Wayne A Phillips
Ptentm1Hwu,
phosphatase and tensin homolog; targeted mutation 1, Hong Wu
Copyright: This image is from Kinross KM, J Clin Invest 2012 Feb 1;122(2):553-7 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright.
J:184382
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Caption: Urothelial hyperplasia and increased apoptosis in bladder epithelium of Ptentm2Mak/Ptentm2Mak Stk11tm1Keis/Stk11tm1Keis Tg(Cyp1a1-cre/ERT)1Dwi/0 mice
(details)
Represented Alleles:
Ptentm2Mak,
phosphatase and tensin homolog; targeted mutation 2, Tak W Mak
Stk11tm1Keis,
serine/threonine kinase 11; targeted mutation 1, Kei Sakamoto
Tg(Cyp1a1-cre/ERT)1Dwi,
transgene insertion 1, Douglas J Winton
Copyright: This image is from Shorning BY, PLoS One 2011;6(1):e16209, and is displayed under the terms of the Creative Commons Attribution 4.0 International License.
J:169565
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/05/2024 MGI 6.24 |
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