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Phenotype Images associated with this Gene
Symbol
Name
ID 		Adam17
a disintegrin and metallopeptidase domain 17
MGI:1096335


6 phenotype image(s) for Adam17 alleles
Showing image(s) 1 to 6
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Caption: Failure of eyelid closure, enlarged aortic, pulmonic, and tricuspid heart valves, and enlarged zone of hypertrophic chondrocytes in growth plates of Rhbdf1tm1b(EUCOMM)Wtsi/Rhbdf1tm1b(EUCOMM)Wtsi Rhbdf2tm1Mak/Rhbdf2tm1Mak (iR1/2-/-) and Adam17tm1.1Bbl/Adam17tm1.1Bbl mice. (details)
Represented Alleles:
Adam17tm1.1Bbl, a disintegrin and metallopeptidase domain 17; targeted mutation 1.1, Carl P Blobel
Rhbdf1tm1b(EUCOMM)Wtsi, rhomboid 5 homolog 1; targeted mutation 1b, Wellcome Trust Sanger Institute
Rhbdf2tm1Mak, rhomboid 5 homolog 2; targeted mutation 1, Tak Mak
Copyright: This image is from Li X, Proc Natl Acad Sci U S A 2015 May 12;112(19):6080-5. Copyright 2015 National Academy of Sciences, U.S.A. J:221411
Caption: Thickened pulmonic valve leaflets and growth plate abnormality inRhbdf1tm1b(EUCOMM)Wtsi/Rhbdf1tm1b(EUCOMM)Wtsi Rhbdf2tm1Mak/Rhbdf2tm1Mak (iR1/2-/-) and Adam17tm1.1Bbl/Adam17tm1.1Bbl mice (details)
Represented Alleles:
Adam17tm1.1Bbl, a disintegrin and metallopeptidase domain 17; targeted mutation 1.1, Carl P Blobel
Rhbdf1tm1b(EUCOMM)Wtsi, rhomboid 5 homolog 1; targeted mutation 1b, Wellcome Trust Sanger Institute
Rhbdf2tm1Mak, rhomboid 5 homolog 2; targeted mutation 1, Tak Mak
Copyright: This image is from Li X, Proc Natl Acad Sci U S A 2015 May 12;112(19):6080-5. Copyright 2015 National Academy of Sciences, U.S.A. J:221411
Caption: Adam17tm1Imx/Adam17tm1Imx embryos develop internal hemorrhage (details)
Represented Alleles:
Adam17tm1Imx, a disintegrin and metallopeptidase domain 17; targeted mutation 1, Immunex
Copyright: This image is from Canault M, PLoS One 2010;5(10):e13433, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:166217
Caption: Vascular defects and hemorrhage in Adam17tm1Imx/Adam17tm1Imx embryos (details)
Represented Alleles:
Adam17tm1Imx, a disintegrin and metallopeptidase domain 17; targeted mutation 1, Immunex
Copyright: This image is from Canault M, PLoS One 2010;5(10):e13433, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:166217
Caption: Vascualr abnormalities in Adam17tm1Imx/Adam17tm1Imx embryos (details)
Represented Alleles:
Adam17tm1Imx, a disintegrin and metallopeptidase domain 17; targeted mutation 1, Immunex
Copyright: This image is from Canault M, PLoS One 2010;5(10):e13433, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:166217
Caption: Abnormal fusion of branches in Adam17tm1Imx/Adam17tm1Imx cranial vessels (details)
Represented Alleles:
Adam17tm1Imx, a disintegrin and metallopeptidase domain 17; targeted mutation 1, Immunex
Copyright: This image is from Canault M, PLoS One 2010;5(10):e13433, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:166217
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/19/2024
MGI 6.24 		The Jackson Laboratory