Phenotype Images associated with this Gene

About Help FAQ

Phenotype Images associated with this Gene

Symbol
Name
ID

Ercc6
excision repair cross-complementing rodent repair deficiency, complementation group 6
MGI:1100494

Click on thumbnail to view full size image with links to phenotype annotations.
Click on allele symbol for full phenotype details.

	Caption: Microglia activation in the white matter in Ercc2, Ercc6, and Ercc8 mutants (details) Represented Alleles: Ercc2^{tm2(ERCC2)Jhjh}, excision repair cross-complementing rodent repair deficiency, complementation group 2; targeted mutation 2, Jan H J Hoeijmakers Ercc2^tm3Jhjh, excision repair cross-complementing rodent repair deficiency, complementation group 2; targeted mutation 3, Jan H J Hoeijmakers Ercc6^tm1Gvh, excision repair cross-complementing rodent repair deficiency, complementation group 6; targeted mutation 1, Gijsbertus van der Horst Ercc8^tm1Jhjh, excision repaiross-complementing rodent repair deficiency, complementation group 8; targeted mutation 1, Jan H J Hoeijmakers Xpa^tm1Hvs, xeroderma pigmentosum, complementation group A; targeted mutation 1, Harry van Steeg Copyright: This image is from Jaarsma D, PLoS Genet 2011 Dec;7(12):e1002405, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:179808
	Caption: Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Gvh/Xpa^tm1Hvs Tg(CAG-cre)13Miya/0 mice are severely reduced in size (details) Represented Alleles: Ercc6^tm1Gvh, excision repair cross-complementing rodent repair deficiency, complementation group 6; targeted mutation 1, Gijsbertus van der Horst Tg(CAG-cre)13Miya, transgene insertion 13, Jun-ichi Miyazaki Xpa^tm1Gvh, xeroderma pigmentosum, complementation group A; targeted mutation 1, Gijsbertus T J van der Horst Xpa^tm1Hvs, xeroderma pigmentosum, complementation group A; targeted mutation 1, Harry van Steeg Copyright: This image is from Jaarsma D, PLoS Genet 2011 Dec;7(12):e1002405, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:179808
	Caption: Dilated ventricles and brain atrophy in Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Gvh/Xpa^tm1Hvs Tg(Camk2a-cre)1Szi/0 mice (details) Represented Alleles: Ercc6^tm1Gvh, excision repair cross-complementing rodent repair deficiency, complementation group 6; targeted mutation 1, Gijsbertus van der Horst Tg(Camk2a-cre)1Szi, transgene insertion 1, Scott Zeitlin Xpa^tm1Gvh, xeroderma pigmentosum, complementation group A; targeted mutation 1, Gijsbertus T J van der Horst Xpa^tm1Hvs, xeroderma pigmentosum, complementation group A; targeted mutation 1, Harry van Steeg Copyright: This image is from Jaarsma D, PLoS Genet 2011 Dec;7(12):e1002405, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:179808
	Caption: Neurodegenerative changes in Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Gvh/Xpa^tm1Hvs Tg(Camk2a-cre)1Szi/0 brains (details) Represented Alleles: Ercc6^tm1Gvh, excision repair cross-complementing rodent repair deficiency, complementation group 6; targeted mutation 1, Gijsbertus van der Horst Tg(Camk2a-cre)1Szi, transgene insertion 1, Scott Zeitlin Xpa^tm1Gvh, xeroderma pigmentosum, complementation group A; targeted mutation 1, Gijsbertus T J van der Horst Xpa^tm1Hvs, xeroderma pigmentosum, complementation group A; targeted mutation 1, Harry van Steeg Copyright: This image is from Jaarsma D, PLoS Genet 2011 Dec;7(12):e1002405, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:179808
	Caption: Neurodegenerative changes in Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Gvh/Xpa^tm1Hvs Tg(Pcp2-cre)2Mpin/0 mice (details) Represented Alleles: Ercc6^tm1Gvh, excision repair cross-complementing rodent repair deficiency, complementation group 6; targeted mutation 1, Gijsbertus van der Horst Tg(Pcp2-cre)2Mpin, transgene insertion 2, Max-Planck-Institute of Neurobiology Xpa^tm1Gvh, xeroderma pigmentosum, complementation group A; targeted mutation 1, Gijsbertus T J van der Horst Xpa^tm1Hvs, xeroderma pigmentosum, complementation group A; targeted mutation 1, Harry van Steeg Copyright: This image is from Jaarsma D, PLoS Genet 2011 Dec;7(12):e1002405, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:179808
	Caption: Microglia activation in the white matter of Ercc6^tm1Gvh/Ercc6^tm1Gvh mice (details) Represented Alleles: Ercc6^tm1Gvh, excision repair cross-complementing rodent repair deficiency, complementation group 6; targeted mutation 1, Gijsbertus van der Horst Copyright: This image is from Jaarsma D, PLoS Genet 2011 Dec;7(12):e1002405, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:179808
	Caption: Weight loss in Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Gvh/Xpa^tm1Hvs Tg(Camk2a-cre)1Szi/0 mice (details) Represented Alleles: Ercc6^tm1Gvh, excision repair cross-complementing rodent repair deficiency, complementation group 6; targeted mutation 1, Gijsbertus van der Horst Tg(Camk2a-cre)1Szi, transgene insertion 1, Scott Zeitlin Xpa^tm1Gvh, xeroderma pigmentosum, complementation group A; targeted mutation 1, Gijsbertus T J van der Horst Xpa^tm1Hvs, xeroderma pigmentosum, complementation group A; targeted mutation 1, Harry van Steeg Copyright: This image is from Jaarsma D, PLoS Genet 2011 Dec;7(12):e1002405, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:179808
	Caption: Brain atrophy after forebrain neuron-specific knockout of Xpa in Ercc6^tm1Gvh/Ercc6^tm1Gvh mice (details) Represented Alleles: Ercc6^tm1Gvh, excision repair cross-complementing rodent repair deficiency, complementation group 6; targeted mutation 1, Gijsbertus van der Horst Tg(Camk2a-cre)1Szi, transgene insertion 1, Scott Zeitlin Xpa^tm1Gvh, xeroderma pigmentosum, complementation group A; targeted mutation 1, Gijsbertus T J van der Horst Xpa^tm1Hvs, xeroderma pigmentosum, complementation group A; targeted mutation 1, Harry van Steeg Copyright: This image is from Jaarsma D, PLoS Genet 2011 Dec;7(12):e1002405, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:179808
	Caption: Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Hvs/Xpa^tm1Hvs mice display postnatal growth retardation (details) Represented Alleles: Ercc6^tm1Gvh, excision repair cross-complementing rodent repair deficiency, complementation group 6; targeted mutation 1, Gijsbertus van der Horst Xpa^tm1Hvs, xeroderma pigmentosum, complementation group A; targeted mutation 1, Harry van Steeg Copyright: This image is from van der Pluijm I, PLoS Biol 2006 Dec 12;5(1):e2, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:122013
	Caption: Skeletal and neurological abnormalities in Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Hvs/Xpa^tm1Hvs mice (details) Represented Alleles: Ercc6^tm1Gvh, excision repair cross-complementing rodent repair deficiency, complementation group 6; targeted mutation 1, Gijsbertus van der Horst Xpa^tm1Hvs, xeroderma pigmentosum, complementation group A; targeted mutation 1, Harry van Steeg Copyright: This image is from van der Pluijm I, PLoS Biol 2006 Dec 12;5(1):e2, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:122013

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24