About   Help   FAQ
Phenotype Images associated with this Gene
Symbol
Name
ID 		Med1
mediator complex subunit 1
MGI:1100846


10 phenotype image(s) for Med1 alleles
Showing image(s) 1 to 10
Click on thumbnail to view full size image with links to phenotype annotations.
Click on allele symbol for full phenotype details.

Caption: Enlarged, flaccid and flabby hearts in Med1tm2Jkr/Med1tm2Jkr Tg(Myh6-cre)2182Mds/0 mice by E25. (details)
Represented Alleles:
Med1tm2Jkr, mediator complex subunit 1; targeted mutation 2, Janardan K Reddy
Copyright: This image is from Jia Y, PLoS One 2016;11(8):e0160755, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:243730
Caption: Heart sections of Med1tm2Jkr/Med1tm2Jkr Tg(Myh6-cre)2182Mds/0 heart reveal thinning of ventricular walls and dilation of chambers. (details)
Represented Alleles:
Med1tm2Jkr, mediator complex subunit 1; targeted mutation 2, Janardan K Reddy
Copyright: This image is from Jia Y, PLoS One 2016;11(8):e0160755, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:243730
Caption: Cardiac fibrosis, increased cardiomyocyte apoptosis and mitochondrial damage in Med1tm2Jkr/Med1tm2Jkr Tg(Myh6-cre)2182Mds/0 mouse heart (details)
Represented Alleles:
Med1tm2Jkr, mediator complex subunit 1; targeted mutation 2, Janardan K Reddy
Tg(Myh6-cre)2182Mds, transgene insertion 2182, Michael D Schneider
Copyright: This image is from Jia Y, PLoS One 2016;11(8):e0160755, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:243730
Caption: The Med1tm2Jkr/Med1tm2Jkr A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+ mouse heart is flaccid and flabby after tamoxifen induction. (details)
Represented Alleles:
A1cfTg(Myh6-cre/Esr1*)1Jmk, APOBEC1 complementation factor; transgene insertion 1, Jeffery D Molkentin
Med1tm2Jkr, mediator complex subunit 1; targeted mutation 2, Janardan K Reddy
Copyright: This image is from Jia Y, PLoS One 2016;11(8):e0160755, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:243730
Caption: Cardiac fibrosis in Med1tm2Jkr/Med1tm2Jkr A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+ mouse heart (details)
Represented Alleles:
A1cfTg(Myh6-cre/Esr1*)1Jmk, APOBEC1 complementation factor; transgene insertion 1, Jeffery D Molkentin
Med1tm2Jkr, mediator complex subunit 1; targeted mutation 2, Janardan K Reddy
Tg(Myh6-cre)2182Mds, transgene insertion 2182, Michael D Schneider
Copyright: This image is from Jia Y, PLoS One 2016;11(8):e0160755, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:243730
Caption: Cardiovascular development defects in Med1tm1Jkr/Med1tm1Jkr embryos (details)
Represented Alleles:
Med1tm1Jkr, mediator complex subunit 1; targeted mutation 1, Janardan K Reddy
Copyright: This image is from Crawford SE, J Biol Chem 2002 Feb 1;277(5):3585-92 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:74328
Caption: Defective angiogenesis in Med1tm1Jkr/Med1tm1Jkr embryos (details)
Represented Alleles:
Med1tm1Jkr, mediator complex subunit 1; targeted mutation 1, Janardan K Reddy
Copyright: This image is from Crawford SE, J Biol Chem 2002 Feb 1;277(5):3585-92 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:74328
Caption: Developmental eye abnormalities in Med1tm1Jkr/Med1tm1Jkr embryos (details)
Represented Alleles:
Med1tm1Jkr, mediator complex subunit 1; targeted mutation 1, Janardan K Reddy
Copyright: This image is from Crawford SE, J Biol Chem 2002 Feb 1;277(5):3585-92 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:74328
Caption: Liver of Med1tm1Jkr/Med1tm1Jkr embryos lacks mature megakaryocytes (details)
Represented Alleles:
Med1tm1Jkr, mediator complex subunit 1; targeted mutation 1, Janardan K Reddy
Copyright: This image is from Crawford SE, J Biol Chem 2002 Feb 1;277(5):3585-92 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:74328
Caption: Histological and ultrastructural alterations in Med1tm1Jkr/Med1tm1Jkr placenta (details)
Represented Alleles:
Med1tm1Jkr, mediator complex subunit 1; targeted mutation 1, Janardan K Reddy
Copyright: This image is from Zhu Y, J Biol Chem 2000 May 19;275(20):14779-82 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:62272
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory