Phenotype Images associated with this Gene

About Help FAQ

Phenotype Images associated with this Gene

Symbol
Name
ID

Crx
cone-rod homeobox
MGI:1194883

Click on thumbnail to view full size image with links to phenotype annotations.
Click on allele symbol for full phenotype details.

	Caption: Crx^tm1.1Smgc/Crx^tm1.1Smgc, Crx^tm2.1Smgc/Crx^tm2.1Smgc, and Crx^tm1Clc/Crx^tm1Clc mice develop Leber Congenital Amaurosis-like retinopathy (details) Represented Alleles: Crx^tm1.1Smgc, cone-rod homeobox; targeted mutation 1.1, Shiming Chen Crx^tm1Clc, cone-rod homeobox; targeted mutation 1, Constance L Cepko Crx^tm2.1Smgc, cone-rod homeobox; targeted mutation 2.1, Shiming Chen Copyright: This image is from Tran NM, PLoS Genet 2014 Feb;10(2):e1004111, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:211011
	Caption: Crx^tm1.1Smgc/Crx⁺ but not Crx^tm2.1Smgc/Crx⁺ develop dominant retinopathy (details) Represented Alleles: Crx^tm1.1Smgc, cone-rod homeobox; targeted mutation 1.1, Shiming Chen Crx^tm2.1Smgc, cone-rod homeobox; targeted mutation 2.1, Shiming Chen Copyright: This image is from Tran NM, PLoS Genet 2014 Feb;10(2):e1004111, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:211011
	Caption: Rod outer segment abnormalities in Crx^tm1.1Smgc/Crx⁺ and Crx^tm1Smgc/Crx⁺ mice (details) Represented Alleles: Crx^tm1.1Smgc, cone-rod homeobox; targeted mutation 1.1, Shiming Chen Crx^tm1Smgc, cone-rod homeobox; targeted mutation 1, Shiming Chen Copyright: This image is from Tran NM, PLoS Genet 2014 Feb;10(2):e1004111, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:211011
	Caption: Crx^tm1.1Smgc/Crx⁺, Crx^tm1Smgc/Crx⁺ and Crx^tm2.1Smgc/Crx⁺ mice display abnormal cone nuclear localization in developing and adult retina (details) Represented Alleles: Crx^tm1.1Smgc, cone-rod homeobox; targeted mutation 1.1, Shiming Chen Crx^tm1Smgc, cone-rod homeobox; targeted mutation 1, Shiming Chen Crx^tm2.1Smgc, cone-rod homeobox; targeted mutation 2.1, Shiming Chen Copyright: This image is from Tran NM, PLoS Genet 2014 Feb;10(2):e1004111, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:211011
	Caption: Photoreceptor abnormalities in Crx^Rip/Crx⁺, Crx^Rip/Crx^Rip, and Crx^tm1Clc/Crx^tm1Clc retinas (details) Represented Alleles: Crx^Rip, cone-rod homeobox; retina with immature photoreceptors Crx^tm1Clc, cone-rod homeobox; targeted mutation 1, Constance L Cepko Copyright: This image is from Roger JE, J Clin Invest 2014 Jan 2;(): and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:203337
	Caption: Abnormal photoreceptor segments in Crx^Rip/Crx⁺, Crx^Rip/Crx^Rip, and Crx^tm1Clc/Crx^tm1Clc mice (details) Represented Alleles: Crx^Rip, cone-rod homeobox; retina with immature photoreceptors Crx^tm1Clc, cone-rod homeobox; targeted mutation 1, Constance L Cepko Copyright: This image is from Roger JE, J Clin Invest 2014 Jan 2;(): and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:203337
	Caption: Crx^Rip/Crx⁺ retinal photoreceptors lack outer segments and possess very short inner segments (details) Represented Alleles: Crx^Rip, cone-rod homeobox; retina with immature photoreceptors Copyright: This image is from Roger JE, J Clin Invest 2014 Jan 2;(): and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:203337
	Caption: Outer retina microscopy of Crx^tm1Clc/Crx^tm1Clc mice (details) Represented Alleles: Crx^tm1Clc, cone-rod homeobox; targeted mutation 1, Constance L Cepko Copyright: This image is from Morrow EM, BMC Neurosci 2005 Jan 27;6(1):5, an open-access article, licensee BioMed Central Ltd. J:95886
	Caption: Outer segment micrograph of Crx^tm1Clc/Crx^tm1Clc retina (details) Represented Alleles: Crx^tm1Clc, cone-rod homeobox; targeted mutation 1, Constance L Cepko Copyright: This image is from Morrow EM, BMC Neurosci 2005 Jan 27;6(1):5, an open-access article, licensee BioMed Central Ltd. J:95886
	Caption: Crx^tm1Clc/Crx^tm1Clc retina and outer segment layer micrographs at P21 and P10 (details) Represented Alleles: Crx^tm1Clc, cone-rod homeobox; targeted mutation 1, Constance L Cepko Copyright: This image is from Morrow EM, BMC Neurosci 2005 Jan 27;6(1):5, an open-access article, licensee BioMed Central Ltd. J:95886

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/03/2024 MGI 6.24