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Phenotype Images associated with this Gene
Symbol
Name
ID
Crx
cone-rod homeobox
MGI:1194883


14 phenotype image(s) for Crx alleles
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Caption: Crxtm1.1Smgc/Crxtm1.1Smgc, Crxtm2.1Smgc/Crxtm2.1Smgc, and Crxtm1Clc/Crxtm1Clc mice develop Leber Congenital Amaurosis-like retinopathy (details)
Represented Alleles:
Crxtm1.1Smgc, cone-rod homeobox; targeted mutation 1.1, Shiming Chen
Crxtm1Clc, cone-rod homeobox; targeted mutation 1, Constance L Cepko
Crxtm2.1Smgc, cone-rod homeobox; targeted mutation 2.1, Shiming Chen
Copyright: This image is from Tran NM, PLoS Genet 2014 Feb;10(2):e1004111, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:211011
Caption: Crxtm1.1Smgc/Crx+ but not Crxtm2.1Smgc/Crx+ develop dominant retinopathy (details)
Represented Alleles:
Crxtm1.1Smgc, cone-rod homeobox; targeted mutation 1.1, Shiming Chen
Crxtm2.1Smgc, cone-rod homeobox; targeted mutation 2.1, Shiming Chen
Copyright: This image is from Tran NM, PLoS Genet 2014 Feb;10(2):e1004111, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:211011
Caption: Rod outer segment abnormalities in Crxtm1.1Smgc/Crx+ and Crxtm1Smgc/Crx+ mice (details)
Represented Alleles:
Crxtm1.1Smgc, cone-rod homeobox; targeted mutation 1.1, Shiming Chen
Crxtm1Smgc, cone-rod homeobox; targeted mutation 1, Shiming Chen
Copyright: This image is from Tran NM, PLoS Genet 2014 Feb;10(2):e1004111, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:211011
Caption: Crxtm1.1Smgc/Crx+, Crxtm1Smgc/Crx+ and Crxtm2.1Smgc/Crx+ mice display abnormal cone nuclear localization in developing and adult retina (details)
Represented Alleles:
Crxtm1.1Smgc, cone-rod homeobox; targeted mutation 1.1, Shiming Chen
Crxtm1Smgc, cone-rod homeobox; targeted mutation 1, Shiming Chen
Crxtm2.1Smgc, cone-rod homeobox; targeted mutation 2.1, Shiming Chen
Copyright: This image is from Tran NM, PLoS Genet 2014 Feb;10(2):e1004111, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:211011
Caption: Photoreceptor abnormalities in CrxRip/Crx+, CrxRip/CrxRip, and Crxtm1Clc/Crxtm1Clc retinas (details)
Represented Alleles:
CrxRip, cone-rod homeobox; retina with immature photoreceptors
Crxtm1Clc, cone-rod homeobox; targeted mutation 1, Constance L Cepko
Copyright: This image is from Roger JE, J Clin Invest 2014 Jan 2;(): and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:203337
Caption: Abnormal photoreceptor segments in CrxRip/Crx+, CrxRip/CrxRip, and Crxtm1Clc/Crxtm1Clc mice (details)
Represented Alleles:
CrxRip, cone-rod homeobox; retina with immature photoreceptors
Crxtm1Clc, cone-rod homeobox; targeted mutation 1, Constance L Cepko
Copyright: This image is from Roger JE, J Clin Invest 2014 Jan 2;(): and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:203337
Caption: CrxRip/Crx+ retinal photoreceptors lack outer segments and possess very short inner segments (details)
Represented Alleles:
CrxRip, cone-rod homeobox; retina with immature photoreceptors
Copyright: This image is from Roger JE, J Clin Invest 2014 Jan 2;(): and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:203337
Caption: Outer retina microscopy of Crxtm1Clc/Crxtm1Clc mice (details)
Represented Alleles:
Crxtm1Clc, cone-rod homeobox; targeted mutation 1, Constance L Cepko
Copyright: This image is from Morrow EM, BMC Neurosci 2005 Jan 27;6(1):5, an open-access article, licensee BioMed Central Ltd. J:95886
Caption: Outer segment micrograph of Crxtm1Clc/Crxtm1Clc retina (details)
Represented Alleles:
Crxtm1Clc, cone-rod homeobox; targeted mutation 1, Constance L Cepko
Copyright: This image is from Morrow EM, BMC Neurosci 2005 Jan 27;6(1):5, an open-access article, licensee BioMed Central Ltd. J:95886
Caption: Crxtm1Clc/Crxtm1Clc retina and outer segment layer micrographs at P21 and P10 (details)
Represented Alleles:
Crxtm1Clc, cone-rod homeobox; targeted mutation 1, Constance L Cepko
Copyright: This image is from Morrow EM, BMC Neurosci 2005 Jan 27;6(1):5, an open-access article, licensee BioMed Central Ltd. J:95886

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory