Phenotype Images associated with this Gene

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Phenotype Images associated with this Gene

Symbol
Name
ID

Pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
MGI:1206581

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	Caption: Ovary tumors in Pik3ca^tm1.1Waph/Pik3ca^tm1.1Waph Pten^tm1Hwu/Pten^tm1Hwu mice (details) Represented Alleles: Pik3ca^tm1.1Waph, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; targeted mutation 1.1, Wayne A Phillips Pten^tm1Hwu, phosphatase and tensin homolog; targeted mutation 1, Hong Wu Copyright: This image is from Kinross KM, J Clin Invest 2012 Feb 1;122(2):553-7 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:184382
	Caption: Hyperproliferation of the ovarian surface epithelium in Pik3ca^tm1.1Waph/Pik3ca^tm1.1Waph mice (details) Represented Alleles: Pik3ca^tm1.1Waph, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; targeted mutation 1.1, Wayne A Phillips Copyright: This image is from Kinross KM, J Clin Invest 2012 Feb 1;122(2):553-7 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:184382
	Caption: Tg(Amhr2-Pik3ca,-GFP)#Lzh/0 females exhibit ovarian surface epithelium hyperplasia (details) Represented Alleles:* Tg(Amhr2-Pik3ca,-GFP)#Lzh, transgene insertion, Lin Zhang Copyright:* This image is from Liang S, PLoS ONE 2009;4(1):e4295, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:144834
	Caption: Hemorrhage is observed in Pik3ca^tm1Nbm/Pik3ca^tm1Nbm embryos (details) Represented Alleles: Pik3ca^tm1Nbm, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; targeted mutation 1, Robert L Nussbaum Copyright: This image is from Bi L, J Biol Chem 1999 Apr 16;274(16):10963-8 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:54237
	Caption: A decrease in cell proliferation is observed in Pik3ca^tm1Nbm/Pik3ca^tm1Nbm embryos (details) Represented Alleles: Pik3ca^tm1Nbm, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; targeted mutation 1, Robert L Nussbaum Copyright: This image is from Bi L, J Biol Chem 1999 Apr 16;274(16):10963-8 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:54237

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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