Symbol Name ID |
Ccdc39
coiled-coil domain containing 39 MGI:1289263 |
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Caption: Color flow spectral Doppler penetration is not very good. Imaging of mutant 2025-005-1 (E14.5) in the sagittal view shows two great arteries originating from RV primarily, suggesting DORV
Click thumbnail to play movie. (details) Represented Alleles:
b2b2025Clo,
Mutant line 2025; Bench to Bassinet Program (B2B/CVDC), mutation 2025 Cecilia Lo
Ccdc39b2b2025.1Clo,
coiled-coil domain containing 39; Bench to Bassinet Program (B2B/CVDC) mutation 2025, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: EFIC Summary
(details)
Represented Alleles:
Ccdc39b2b1735Clo,
coiled-coil domain containing 39; Bench to Bassinet Program (B2B/CVDC) mutation 1735, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant 2025-003-1 (E15.5) exhibits levocardia with malalignment of the great arteries with abnormal aortic arch shown by EFIC histology to comprise of an interruption between right brachiocephalic artery and left carotid artery with neck artery branching pattern remaining left sided. Also diagnosed as non-compaction by EFIC.
(details)
Represented Alleles:
b2b2025Clo,
Mutant line 2025; Bench to Bassinet Program (B2B/CVDC), mutation 2025 Cecilia Lo
Ccdc39b2b2025.1Clo,
coiled-coil domain containing 39; Bench to Bassinet Program (B2B/CVDC) mutation 2025, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Serial 2D EFIC image stack of 1735-002-LC in the coronal plane reveals mirror image dextrocardia
Click thumbnail to play movie. (details) Represented Alleles:
Ccdc39b2b1735Clo,
coiled-coil domain containing 39; Bench to Bassinet Program (B2B/CVDC) mutation 1735, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant 2025-003-1 (E15.5) exhibits heterotaxy with levocardia and dextrogastria
(details)
Represented Alleles:
b2b2025Clo,
Mutant line 2025; Bench to Bassinet Program (B2B/CVDC), mutation 2025 Cecilia Lo
Ccdc39b2b2025.1Clo,
coiled-coil domain containing 39; Bench to Bassinet Program (B2B/CVDC) mutation 2025, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant 1735-002-LC exhibits micrognathia and short snout
(details)
Represented Alleles:
Ccdc39b2b1735Clo,
coiled-coil domain containing 39; Bench to Bassinet Program (B2B/CVDC) mutation 1735, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant 2025-003-1 (E15.5) exhibits heterotaxy with dextrogastria, right-sided pancreas, and asplenia
(details)
Represented Alleles:
b2b2025Clo,
Mutant line 2025; Bench to Bassinet Program (B2B/CVDC), mutation 2025 Cecilia Lo
Ccdc39b2b2025.1Clo,
coiled-coil domain containing 39; Bench to Bassinet Program (B2B/CVDC) mutation 2025, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: EFIC Summary
(details)
Represented Alleles:
b2b2025Clo,
Mutant line 2025; Bench to Bassinet Program (B2B/CVDC), mutation 2025 Cecilia Lo
Ccdc39b2b2025.1Clo,
coiled-coil domain containing 39; Bench to Bassinet Program (B2B/CVDC) mutation 2025, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Serial EFIC image stack in coronal plane of mutant 2025-003-1 (E15.5) shows DORV, unbalanced AVSD {S,D,D}, IAA (type C), bicuspid aortic valve, small LV, ventricular non-compaction, and left atrial isomerism
Click thumbnail to play movie. (details) Represented Alleles:
b2b2025Clo,
Mutant line 2025; Bench to Bassinet Program (B2B/CVDC), mutation 2025 Cecilia Lo
Ccdc39b2b2025.1Clo,
coiled-coil domain containing 39; Bench to Bassinet Program (B2B/CVDC) mutation 2025, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant 2025-005-3 (E14.5) is diagnosed with heterotaxy with dextroversion, left lung isomerism (1R/1L) and overriding aorta which is confirmed by EFIC
(details)
Represented Alleles:
b2b2025Clo,
Mutant line 2025; Bench to Bassinet Program (B2B/CVDC), mutation 2025 Cecilia Lo
Ccdc39b2b2025.1Clo,
coiled-coil domain containing 39; Bench to Bassinet Program (B2B/CVDC) mutation 2025, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/17/2024 MGI 6.24 |
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