Symbol Name ID |
Slit3
slit guidance ligand 3 MGI:1315202 |
Caption: Mutant 2362-004-1 (E16.5) exhibits ectopia cordis, ventricular non-compaction, and gastroschisis with a body wall closure defect
(details)
Represented Alleles:
b2b2362Clo,
Mutant line 2362; Bench to Bassinet Program (B2B/CVDC), mutation 2362 Cecilia Lo
Slit3b2b2362.1Clo,
slit guidance ligand 3; Bench to Bassinet Program (B2B/CVDC) mutation 2362, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant 2362-004-1 (E16.5) with ectopia cortis exhibits DORV with aorta positioned anteriorly (Taussig Bing subtype DORV), which was confirmed by EFIC histology
(details)
Represented Alleles:
b2b2362Clo,
Mutant line 2362; Bench to Bassinet Program (B2B/CVDC), mutation 2362 Cecilia Lo
Slit3b2b2362.1Clo,
slit guidance ligand 3; Bench to Bassinet Program (B2B/CVDC) mutation 2362, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: EFIC Summary
(details)
Represented Alleles:
b2b2362Clo,
Mutant line 2362; Bench to Bassinet Program (B2B/CVDC), mutation 2362 Cecilia Lo
Slit3b2b2362.1Clo,
slit guidance ligand 3; Bench to Bassinet Program (B2B/CVDC) mutation 2362, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Serial 2D EFIC image stack in the coronal plane of 2362-004-1 (E16.5) reveals Taussig-Bing type DORV, AVSD, and ventricular non-compaction
Click thumbnail to play movie. (details) Represented Alleles:
b2b2362Clo,
Mutant line 2362; Bench to Bassinet Program (B2B/CVDC), mutation 2362 Cecilia Lo
Slit3b2b2362.1Clo,
slit guidance ligand 3; Bench to Bassinet Program (B2B/CVDC) mutation 2362, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Ultrasound imaging of mutant 2362-004 (E16.5) in the sagittal view shows the heart out of the chest, suggesting ectopia cordis
Click thumbnail to play movie. (details) Represented Alleles:
b2b2362Clo,
Mutant line 2362; Bench to Bassinet Program (B2B/CVDC), mutation 2362 Cecilia Lo
Slit3b2b2362.1Clo,
slit guidance ligand 3; Bench to Bassinet Program (B2B/CVDC) mutation 2362, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant embryo at E16.5 show abnormal severely hypoplastic kidney.
(details)
Represented Alleles:
b2b2362Clo,
Mutant line 2362; Bench to Bassinet Program (B2B/CVDC), mutation 2362 Cecilia Lo
Slit3b2b2362.1Clo,
slit guidance ligand 3; Bench to Bassinet Program (B2B/CVDC) mutation 2362, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant 2362-004-2 (E16.5) was diagnosed as having DORV by fetal echocardiography, later confirmed by EFIC histology
(details)
Represented Alleles:
b2b2362Clo,
Mutant line 2362; Bench to Bassinet Program (B2B/CVDC), mutation 2362 Cecilia Lo
Slit3b2b2362.1Clo,
slit guidance ligand 3; Bench to Bassinet Program (B2B/CVDC) mutation 2362, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: EFIC Summary
(details)
Represented Alleles:
b2b2362Clo,
Mutant line 2362; Bench to Bassinet Program (B2B/CVDC), mutation 2362 Cecilia Lo
Slit3b2b2362.1Clo,
slit guidance ligand 3; Bench to Bassinet Program (B2B/CVDC) mutation 2362, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Serial 2D EFIC image stack in the coronal plane of 2362-004-2 (E16.5) reveals DORV and a subaortic VSD
Click thumbnail to play movie. (details) Represented Alleles:
b2b2362Clo,
Mutant line 2362; Bench to Bassinet Program (B2B/CVDC), mutation 2362 Cecilia Lo
Slit3b2b2362.1Clo,
slit guidance ligand 3; Bench to Bassinet Program (B2B/CVDC) mutation 2362, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant embryo (E16.5) has a few glomerular cysts.
(details)
Represented Alleles:
b2b2362Clo,
Mutant line 2362; Bench to Bassinet Program (B2B/CVDC), mutation 2362 Cecilia Lo
Slit3b2b2362.1Clo,
slit guidance ligand 3; Bench to Bassinet Program (B2B/CVDC) mutation 2362, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/17/2024 MGI 6.24 |
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