Symbol Name ID |
Slit2
slit guidance ligand 2 MGI:1315205 |
Caption: Mutant 1200-007-2 (E17) shows dextrocardia with abnormal arch and dilated ductus arteriosus
(details)
Represented Alleles:
b2b1200Clo,
Mutant line 1200; Bench to Bassinet Program (B2B/CVDC), mutation 1200 Cecilia Lo
Slit2b2b1200.1Clo,
slit guidance ligand 2; Bench to Bassinet Program (B2B/CVDC) mutation 1200, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
|
|
Caption: Mutant 1200-007-2 (E17) shows abnormal arch with dilated ductus arteriosus
(details)
Represented Alleles:
b2b1200Clo,
Mutant line 1200; Bench to Bassinet Program (B2B/CVDC), mutation 1200 Cecilia Lo
Slit2b2b1200.1Clo,
slit guidance ligand 2; Bench to Bassinet Program (B2B/CVDC) mutation 1200, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
|
|
Caption: Mutant 1200-007-2 (E17) shows bilateral duplex kidney, cystic kidney disease, hydronephrosis, and hydroureter
(details)
Represented Alleles:
b2b1200Clo,
Mutant line 1200; Bench to Bassinet Program (B2B/CVDC), mutation 1200 Cecilia Lo
Slit2b2b1200.1Clo,
slit guidance ligand 2; Bench to Bassinet Program (B2B/CVDC) mutation 1200, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
|
|
Caption: EFIC Summary
(details)
Represented Alleles:
b2b1200Clo,
Mutant line 1200; Bench to Bassinet Program (B2B/CVDC), mutation 1200 Cecilia Lo
Slit2b2b1200.1Clo,
slit guidance ligand 2; Bench to Bassinet Program (B2B/CVDC) mutation 1200, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
|
|
Caption: 2D serial EFIC image stacks in the coronal plane of 1200-007-2 reveals perimembranous and 2 muscular VSDs, spongie ventricular wall, dysplastic semilunar valve, hypoplastic transverse aortic arch.
Click thumbnail to play movie. (details) Represented Alleles:
b2b1200Clo,
Mutant line 1200; Bench to Bassinet Program (B2B/CVDC), mutation 1200 Cecilia Lo
Slit2b2b1200.1Clo,
slit guidance ligand 2; Bench to Bassinet Program (B2B/CVDC) mutation 1200, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
|
|
Caption: Hypoplastic transverse arch
(details)
Represented Alleles:
b2b1200Clo,
Mutant line 1200; Bench to Bassinet Program (B2B/CVDC), mutation 1200 Cecilia Lo
Slit2b2b1200.1Clo,
slit guidance ligand 2; Bench to Bassinet Program (B2B/CVDC) mutation 1200, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
|
|
Caption: Mutant 1200-007-2 shows bilateral duplex kidneys and hydroureter
(details)
Represented Alleles:
b2b1200Clo,
Mutant line 1200; Bench to Bassinet Program (B2B/CVDC), mutation 1200 Cecilia Lo
Slit2b2b1200.1Clo,
slit guidance ligand 2; Bench to Bassinet Program (B2B/CVDC) mutation 1200, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
|
|
Caption: Mutant 1200-007-2 shows bilateral duplex or multiplex kidneys
(details)
Represented Alleles:
b2b1200Clo,
Mutant line 1200; Bench to Bassinet Program (B2B/CVDC), mutation 1200 Cecilia Lo
Slit2b2b1200.1Clo,
slit guidance ligand 2; Bench to Bassinet Program (B2B/CVDC) mutation 1200, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
|
|
Caption: Immunofluorescence of ureteric bud
(details)
Represented Alleles:
b2b1200Clo,
Mutant line 1200; Bench to Bassinet Program (B2B/CVDC), mutation 1200 Cecilia Lo
Slit2b2b1200.1Clo,
slit guidance ligand 2; Bench to Bassinet Program (B2B/CVDC) mutation 1200, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
|
|
Caption: Mutant 1200-004-NC exhibit malaligned great arteries.
(details)
Represented Alleles:
b2b1200Clo,
Mutant line 1200; Bench to Bassinet Program (B2B/CVDC), mutation 1200 Cecilia Lo
Slit2b2b1200.1Clo,
slit guidance ligand 2; Bench to Bassinet Program (B2B/CVDC) mutation 1200, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 11/12/2024 MGI 6.24 |
|
|