Phenotype Images associated with this Gene

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Phenotype Images associated with this Gene

Symbol
Name
ID

Ptf1a
pancreas specific transcription factor, 1a
MGI:1328312

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	Caption: Pancreatic fibrosis and acinar-to-ductal metaplasia in Tg(MtTGFA)Lmb/0 (MT-TGFalpha) and Smad4^tm1.1Gsu/Smad4^tm1.1Gsu Ptf1a^{tm1.1(cre)Cvw}/Ptf1a⁺ Tg(MtTGFA)Lmb/0 (STP) mice (details) Represented Alleles: Ptf1a^{tm1.1(cre)Cvw}, pancreas specific transcription factor, 1a; targeted mutation 1.1, Christopher VE Wright Smad4^tm1.1Gsu, SMAD family member 4; targeted mutation 1.1, Gloria H Su Tg(MtTGFA)Lmb, transgene insertion, Glenn Merlino Copyright: This image is from Garcia-Carracedo D, PLoS One 2015;10(3):e0120851, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:229184
	Caption: Increased number of PanIN lesions in the Smad4^tm1.1Gsu/Smad4^tm1.1Gsu Ptf1a^{tm1.1(cre)Cvw}/Ptf1a⁺ Tg(MtTGFA)Lmb/0 (STP) mice compared to Tg(MtTGFA)Lmb/0 (MT-TGFalpha) mice (details) Represented Alleles: Ptf1a^{tm1.1(cre)Cvw}, pancreas specific transcription factor, 1a; targeted mutation 1.1, Christopher VE Wright Smad4^tm1.1Gsu, SMAD family member 4; targeted mutation 1.1, Gloria H Su Tg(MtTGFA)Lmb, transgene insertion, Glenn Merlino Copyright: This image is from Garcia-Carracedo D, PLoS One 2015;10(3):e0120851, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:229184
	Caption: Enhanced pancreatic epithelial expasnion in Smad4^tm1.1Gsu/Smad4^tm1.1Gsu Ptf1a^{tm1.1(cre)Cvw}/Ptf1a⁺ Tg(MtTGFA)Lmb/0 mice compared to Tg(MtTGFA)Lmb/0 mice (details) Represented Alleles: Ptf1a^{tm1.1(cre)Cvw}, pancreas specific transcription factor, 1a; targeted mutation 1.1, Christopher VE Wright Smad4^tm1.1Gsu, SMAD family member 4; targeted mutation 1.1, Gloria H Su Tg(MtTGFA)Lmb, transgene insertion, Glenn Merlino Copyright: This image is from Garcia-Carracedo D, PLoS One 2015;10(3):e0120851, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:229184
	Caption: Aggravated pancreatic fibrosis in Smad4^tm1.1Gsu/Smad4^tm1.1Gsu Ptf1a^{tm1.1(cre)Cvw}/Ptf1a⁺ Tg(MtTGFA)Lmb/0 mice compared to Tg(MtTGFA)Lmb/0 mice (details) Represented Alleles: Ptf1a^{tm1.1(cre)Cvw}, pancreas specific transcription factor, 1a; targeted mutation 1.1, Christopher VE Wright Smad4^tm1.1Gsu, SMAD family member 4; targeted mutation 1.1, Gloria H Su Tg(MtTGFA)Lmb, transgene insertion, Glenn Merlino Copyright: This image is from Garcia-Carracedo D, PLoS One 2015;10(3):e0120851, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:229184
	Caption: Elevated Mucin-6 expression indicates pancreatitis in Smad4^tm1.1Gsu/Smad4^tm1.1Gsu Ptf1a^{tm1.1(cre)Cvw}/Ptf1a⁺ Tg(MtTGFA)Lmb/0 (STP) mice (details) Represented Alleles: Ptf1a^{tm1.1(cre)Cvw}, pancreas specific transcription factor, 1a; targeted mutation 1.1, Christopher VE Wright Smad4^tm1.1Gsu, SMAD family member 4; targeted mutation 1.1, Gloria H Su Tg(MtTGFA)Lmb, transgene insertion, Glenn Merlino Copyright: This image is from Garcia-Carracedo D, PLoS One 2015;10(3):e0120851, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:229184
	Caption: Ataxic gait in Robo3^tm1.1Ache/Robo3^tm1.1Ache Ptf1a^{tm1.1(cre)Cvw}/Ptf1a⁺ mice (details) Represented Alleles: Ptf1a^{tm1.1(cre)Cvw}, pancreas specific transcription factor, 1a; targeted mutation 1.1, Christopher VE Wright Robo3^tm1.1Ache, roundabout guidance receptor 3; targeted mutation 1.1, Alain Chedotal Copyright: This image is from Renier N, PLoS Biol 2010;8(3):e1000325, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:158918
	Caption: Fewer inferior olivary neurons project contralaterally in Robo3^tm1.1Ache/Robo3^tm1.1Ache Ptf1a^{tm1.1(cre)Cvw}/Ptf1a⁺ mice (details) Represented Alleles: Ptf1a^{tm1.1(cre)Cvw}, pancreas specific transcription factor, 1a; targeted mutation 1.1, Christopher VE Wright Robo3^tm1.1Ache, roundabout guidance receptor 3; targeted mutation 1.1, Alain Chedotal Copyright: This image is from Renier N, PLoS Biol 2010;8(3):e1000325, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:158918
	Caption: The structure of the inferior olivary nucleus is disorganized in Robo3^tm1.1Ache/Robo3^tm1.1Ache Ptf1a^{tm1.1(cre)Cvw}/Ptf1a⁺ mice (details) Represented Alleles: Ptf1a^{tm1.1(cre)Cvw}, pancreas specific transcription factor, 1a; targeted mutation 1.1, Christopher VE Wright Robo3^tm1.1Ache, roundabout guidance receptor 3; targeted mutation 1.1, Alain Chedotal Copyright: This image is from Renier N, PLoS Biol 2010;8(3):e1000325, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:158918

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