Symbol Name ID |
Bmp10
bone morphogenetic protein 10 MGI:1338820 |
Caption: Absent vitelline vessels in the yolk sac, stalled vascular development at the primary capillary plexus stage, and arteriovenous malformation in Bmp10tm1Shou/Bmp10tm1Shou embryos
(details)
Represented Alleles:
Bmp10tm1Shou,
bone morphogenetic protein 10; targeted mutation 1, Weinian Shou
Copyright: This image is from Chen H, Proc Natl Acad Sci U S A 2013 Jul 16;110(29):11887-92. Copyright 2013 National Academy of Sciences, U.S.A.
J:222016
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Caption: Bmp10tm1.1(Gdf2)Minh/Bmp10tm1.1(Gdf2)Minh hearts are hypoplastic with thinner ventricular wall and pericardial edema
(details)
Represented Alleles:
Bmp10tm1.1(Gdf2)Minh,
bone morphogenetic protein 10; targeted mutation 1.1, Minhong Yan
Copyright: This image is from Chen H, Proc Natl Acad Sci U S A 2013 Jul 16;110(29):11887-92. Copyright 2013 National Academy of Sciences, U.S.A.
J:222016
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Caption: Hemorrhage, edema, abnormal heart morphology, and ventricular septal defects in Bmp10tm1.1(Gdf2)Minh/Bmp10tm1.1(Gdf2)Minh fetuses
(details)
Represented Alleles:
Bmp10tm1.1(Gdf2)Minh,
bone morphogenetic protein 10; targeted mutation 1.1, Minhong Yan
Copyright: This image is from Chen H, Proc Natl Acad Sci U S A 2013 Jul 16;110(29):11887-92. Copyright 2013 National Academy of Sciences, U.S.A.
J:222016
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Caption: Mutant (E16.5) exhibits a hypoplastic thymus.
(details)
Represented Alleles:
Bmp10b2b2711Clo,
bone morphogenetic protein 10; Bench to Bassinet Program (B2B/CVDC), mutation 2711 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant (E16.5) has parallel outflow tracts, indicating possible DORV which is confirmed by ECM. Mutant also shows hypoplastic PA and hypoplastic lungs.
(details)
Represented Alleles:
Bmp10b2b2711Clo,
bone morphogenetic protein 10; Bench to Bassinet Program (B2B/CVDC), mutation 2711 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: EFIC Summary
(details)
Represented Alleles:
Bmp10b2b2711Clo,
bone morphogenetic protein 10; Bench to Bassinet Program (B2B/CVDC), mutation 2711 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Serial 2D ECM image stack of mutant (E16.5) shows DORV (TOF type), subaortic VSD, and hypoplastic PA.
Click thumbnail to play movie. (details) Represented Alleles:
Bmp10b2b2711Clo,
bone morphogenetic protein 10; Bench to Bassinet Program (B2B/CVDC), mutation 2711 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Color flow spectral Doppler imaging of mutant in the saggital view shows hypoplastic PA with PA retrograde flow, overriding Ao and VSD suggesting Tetralogy of Fallot
Click thumbnail to play movie. (details) Represented Alleles:
Bmp10b2b2711Clo,
bone morphogenetic protein 10; Bench to Bassinet Program (B2B/CVDC), mutation 2711 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Color flow spectral Doppler imaging of mutant in the saggital view shows hypoplastic pulmonary artery
(details)
Represented Alleles:
Bmp10b2b2711Clo,
bone morphogenetic protein 10; Bench to Bassinet Program (B2B/CVDC), mutation 2711 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Color flow spectral Doppler imaging of mutant in the saggital view shows a shunt between left ventricle and right ventricle indicating VSD.
(details)
Represented Alleles:
Bmp10b2b2711Clo,
bone morphogenetic protein 10; Bench to Bassinet Program (B2B/CVDC), mutation 2711 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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