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Phenotype Images associated with this Gene
Symbol
Name
ID
Sufu
SUFU negative regulator of hedgehog signaling
MGI:1345643


15 phenotype image(s) for Sufu alleles
Showing image(s) 1 to 10
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Click on allele symbol for full phenotype details.

Caption: 2D serial EFIC image stack of mutant 273-003-NC in the coronal view reveals DORV {SDD}, suboartic VSD, and non-compaction of the ventricular myocardium, bilateral coronary artery fistula
Click thumbnail to play movie. (details)
Represented Alleles:
Sufub2b273Clo, SUFU negative regulator of hedgehog signaling; Bench to Bassinet Program (B2B/CVDC), mutation 273 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: 2D serial EFIC image stack of mutant 273-003-NK in the coronal view reveals muscular VSD and high take-off coronary arteries
Click thumbnail to play movie. (details)
Represented Alleles:
Sufub2b273Clo, SUFU negative regulator of hedgehog signaling; Bench to Bassinet Program (B2B/CVDC), mutation 273 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: 2D serial EFIC image stack of mutant 273-003-NC in the sagittal view reveals DORV
Click thumbnail to play movie. (details)
Represented Alleles:
Sufub2b273Clo, SUFU negative regulator of hedgehog signaling; Bench to Bassinet Program (B2B/CVDC), mutation 273 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: 2D serial EFIC image stack of mutant 273-003-NE in the coronal view reveals perimembranous VSD
Click thumbnail to play movie. (details)
Represented Alleles:
Sufub2b273Clo, SUFU negative regulator of hedgehog signaling; Bench to Bassinet Program (B2B/CVDC), mutation 273 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Coronal movie of 273-003-NI obtained from micro-CT scan reveals hydrocephalus, perimembranous VSD, overriding aorta and right duplicated kidney
Click thumbnail to play movie. (details)
Represented Alleles:
Sufub2b273Clo, SUFU negative regulator of hedgehog signaling; Bench to Bassinet Program (B2B/CVDC), mutation 273 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: 2D serial EFIC image stack of mutant 273-003-NI in the coronal view reveals perimembranous VSD and overriding aorta
Click thumbnail to play movie. (details)
Represented Alleles:
Sufub2b273Clo, SUFU negative regulator of hedgehog signaling; Bench to Bassinet Program (B2B/CVDC), mutation 273 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Preaxial digit duplication in mutant 273-003-NE (details)
Represented Alleles:
Sufub2b273Clo, SUFU negative regulator of hedgehog signaling; Bench to Bassinet Program (B2B/CVDC), mutation 273 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 273-003-NE with micrognathia and microcephaly with dome shaped head. (details)
Represented Alleles:
Sufub2b273Clo, SUFU negative regulator of hedgehog signaling; Bench to Bassinet Program (B2B/CVDC), mutation 273 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Hindlimb polydactyly with preaxial digit duplication in mutant 273-003-NI (details)
Represented Alleles:
Sufub2b273Clo, SUFU negative regulator of hedgehog signaling; Bench to Bassinet Program (B2B/CVDC), mutation 273 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Microcephaly, micrognathia, and dome shaped head in mutant 273-003-NI (details)
Represented Alleles:
Sufub2b273Clo, SUFU negative regulator of hedgehog signaling; Bench to Bassinet Program (B2B/CVDC), mutation 273 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory