Phenotype Images associated with this Gene

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Phenotype Images associated with this Gene

Symbol
Name
ID

Map3k4
mitogen-activated protein kinase kinase kinase 4
MGI:1346875

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Click on allele symbol for full phenotype details.

	Caption: Exencephaly, spina bifida, mild edema, and gonadal abnormalities with XY gonadal sex reversal in Map3k4^byg/Map3k4^byg embryos (details) Represented Alleles: Map3k4^byg, mitogen-activated protein kinase kinase kinase 4; boygirl Copyright: This image is from Bogani D, PLoS Biol 2009 Sep;7(9):e1000196, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:153050
	Caption: XY gonad in Map3k4^tm1Flv/Map3k4^tm1Flv embryos exhibits overt ovarian morphology (details) Represented Alleles: Map3k4^tm1Flv, mitogen-activated protein kinase kinase kinase 4; targeted mutation 1, Richard A Flavell Copyright: This image is from Bogani D, PLoS Biol 2009 Sep;7(9):e1000196, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:153050
	Caption: XY embryos doubly heterozygous for Map3k4^byg and Del(17)T^hp exhibit a range of defects of gonad development similar to Map3k4^byg homozygotes (details) Represented Alleles: Del(17)T^hp, deletion, Chr 17, T, hairpin tail Map3k4^byg, mitogen-activated protein kinase kinase kinase 4; boygirl Copyright: This image is from Bogani D, PLoS Biol 2009 Sep;7(9):e1000196, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:153050
	Caption: Ovotestis development in Map3k4^tm1Flv/Map3k4⁺ X/Sry^AKR/J embryos, characterised by gonadal poles (brackets) lacking markers of testis development and expressing markers of ovary development (details) Represented Alleles: Map3k4^tm1Flv, mitogen-activated protein kinase kinase kinase 4; targeted mutation 1, Richard A Flavell Sry^AKR/J, sex determining region of Chr Y; sex-determining region of Chr Y- AKR/J Copyright: This image is from Bogani D, PLoS Biol 2009 Sep;7(9):e1000196, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:153050

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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