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Symbol Name ID |
Dnai1
dynein axonemal intermediate chain 1 MGI:1916172 |
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Caption: Dextrocardia with parallel outflow tracts suggestive of DORV (confirmed by EFIC imaging).
(details)
Represented Alleles:
Dnai1b2b284Clo,
dynein axonemal intermediate chain 1; Bench to Bassinet Program (B2B/CVDC), mutation 284 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant 1526-007-NA exhibits heterotaxy with dextrocardia, dual IVC, left lung isomerism (2R/2L), stenotic transverse aortic arch, and thickened ventricular walls which is diagnosed as biventricular hypertrophy by EFIC imaging
(details)
Represented Alleles:
Dnai1b2b1526Clo,
dynein axonemal intermediate chain 1; Bench to Bassinet Program (B2B/CVDC), mutation 1526 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Heterotaxy is indicated by dextrocardia and levogastria
(details)
Represented Alleles:
Dnai1b2b284Clo,
dynein axonemal intermediate chain 1; Bench to Bassinet Program (B2B/CVDC), mutation 284 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: EFIC Summary
(details)
Represented Alleles:
Dnai1b2b1526Clo,
dynein axonemal intermediate chain 1; Bench to Bassinet Program (B2B/CVDC), mutation 1526 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Coronal movie obtained by micro-CT scan reveals dextrocardia {ILL}, TGA, and inverted lung lobation pattern
Click thumbnail to play movie. (details) Represented Alleles:
Dnai1b2b284Clo,
dynein axonemal intermediate chain 1; Bench to Bassinet Program (B2B/CVDC), mutation 284 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Serial 2D EFIC image stack in the coronal plane of 1526-007-NA reveals mirror image dextrocardia, biventricular hypertrophy, stenosis of transverse arch, and dual IVC
Click thumbnail to play movie. (details) Represented Alleles:
Dnai1b2b1526Clo,
dynein axonemal intermediate chain 1; Bench to Bassinet Program (B2B/CVDC), mutation 1526 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: EM micrograph reveals missing ODA within tracheal airway cilia
(details)
Represented Alleles:
Dnai1b2b284Clo,
dynein axonemal intermediate chain 1; Bench to Bassinet Program (B2B/CVDC), mutation 284 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant 1526-007-NA presents with a short snout and microganthia
(details)
Represented Alleles:
Dnai1b2b1526Clo,
dynein axonemal intermediate chain 1; Bench to Bassinet Program (B2B/CVDC), mutation 1526 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: 3D EFIC imaging movie reveals situs inversus totalis {I,L,I}
Click thumbnail to play movie. (details) Represented Alleles:
Dnai1b2b284Clo,
dynein axonemal intermediate chain 1; Bench to Bassinet Program (B2B/CVDC), mutation 284 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant 1526-007-NA shows a malaligned sternum
(details)
Represented Alleles:
Dnai1b2b1526Clo,
dynein axonemal intermediate chain 1; Bench to Bassinet Program (B2B/CVDC), mutation 1526 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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