Symbol Name ID |
Ptk7
PTK7 protein tyrosine kinase 7 MGI:1918711 |
|
Caption: Mutant 2445-003-1 (E16.5) exhibits malaligned great arteries and abnormal aortic arch, which was confirmed as DORV and hypoplastic transverse aorta by EFIC imaging
(details)
Represented Alleles:
Ptk7b2b2445Clo,
PTK7 protein tyrosine kinase 7; Bench to Bassinet Program (B2B/CVDC), mutation 2445 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
|
|
Caption: Mutant 2445-003-1 (E16.5) has cystic kidneys as seen on histology
(details)
Represented Alleles:
Ptk7b2b2445Clo,
PTK7 protein tyrosine kinase 7; Bench to Bassinet Program (B2B/CVDC), mutation 2445 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
|
|
Caption: EFIC Summary
(details)
Represented Alleles:
Ptk7b2b2445Clo,
PTK7 protein tyrosine kinase 7; Bench to Bassinet Program (B2B/CVDC), mutation 2445 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
|
|
Caption: Serial 2D EFIC image stack in the coronal plane of 2445-003-1 (E16.5) reveals DORV, subaortic VSD, mVSD, and hypoplastic transverse aorta
Click thumbnail to play movie. (details) Represented Alleles:
Ptk7b2b2445Clo,
PTK7 protein tyrosine kinase 7; Bench to Bassinet Program (B2B/CVDC), mutation 2445 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
|
|
Caption: Color flow spectral Doppler imaging of mutant 2445-003-1 (E16.5) in the sagittal view shows two great arteries originating from RV primarily, suggesting DORV
Click thumbnail to play movie. (details) Represented Alleles:
Ptk7b2b2445Clo,
PTK7 protein tyrosine kinase 7; Bench to Bassinet Program (B2B/CVDC), mutation 2445 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
|
|
Caption: The kidneys of 2445-003-1 have mild cystic kidney disease
(details)
Represented Alleles:
Ptk7b2b2445Clo,
PTK7 protein tyrosine kinase 7; Bench to Bassinet Program (B2B/CVDC), mutation 2445 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
|
|
Caption: Mutant 2445-007-2 (E17.5) presents with excencephaly, short snout, micrognathia, and no tail
(details)
Represented Alleles:
Ptk7b2b2445Clo,
PTK7 protein tyrosine kinase 7; Bench to Bassinet Program (B2B/CVDC), mutation 2445 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
|
|
Caption: Mutant 2445-007-2 (E17.5) shows spina bifida
(details)
Represented Alleles:
Ptk7b2b2445Clo,
PTK7 protein tyrosine kinase 7; Bench to Bassinet Program (B2B/CVDC), mutation 2445 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
|
|
Caption: Mutant 2445-007-2 (E17.5) exhibits a maligned sternal vertebra
(details)
Represented Alleles:
Ptk7b2b2445Clo,
PTK7 protein tyrosine kinase 7; Bench to Bassinet Program (B2B/CVDC), mutation 2445 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
|
|
Caption: Left kidney of 2445-007-2 has mild cysts or cystic dilations of the tubules
(details)
Represented Alleles:
Ptk7b2b2445Clo,
PTK7 protein tyrosine kinase 7; Bench to Bassinet Program (B2B/CVDC), mutation 2445 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 12/17/2024 MGI 6.24 |
![]() |
|