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Phenotype Images associated with this Gene
Symbol
Name
ID 		Akr1a1
aldo-keto reductase family 1, member A1
MGI:1929955


5 phenotype image(s) for Akr1a1 alleles
Showing image(s) 1 to 5
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Click on allele symbol for full phenotype details.

Caption: Severe loss of bone and fractures in the long bones of Akr1a1Gt(OST222400)Lex/Akr1a1Gt(OST222400)Lex mice (details)
Represented Alleles:
Akr1a1Gt(OST222400)Lex, aldo-keto reductase family 1, member A1; gene trap OST222400, Lexicon Genetics
Copyright: This image is from Gabbay KH, J Biol Chem 2010 Jun 18;285(25):19510-20 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:164548
Caption: Spontaneous bone fractures and loss of trabecular bone in Akr1a1Gt(OST222400)Lex/Akr1a1Gt(OST222400)Lex mice (details)
Represented Alleles:
Akr1a1Gt(OST222400)Lex, aldo-keto reductase family 1, member A1; gene trap OST222400, Lexicon Genetics
Copyright: This image is from Gabbay KH, J Biol Chem 2010 Jun 18;285(25):19510-20 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:164548
Caption: Trabecular bone loss in castrated Akr1a1Gt(OST222400)Lex/Akr1a1Gt(OST222400)Lex males (details)
Represented Alleles:
Akr1a1Gt(OST222400)Lex, aldo-keto reductase family 1, member A1; gene trap OST222400, Lexicon Genetics
Copyright: This image is from Gabbay KH, J Biol Chem 2010 Jun 18;285(25):19510-20 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:164548
Caption: Affected turbinates in castrated Akr1a1Gt(OST222400)Lex/Akr1a1Gt(OST222400)Lex males (details)
Represented Alleles:
Akr1a1Gt(OST222400)Lex, aldo-keto reductase family 1, member A1; gene trap OST222400, Lexicon Genetics
Copyright: This image is from Gabbay KH, J Biol Chem 2010 Jun 18;285(25):19510-20 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:164548
Caption: "Rachitic rosary" phenotype of Gulotm1Mae/Gulotm1Mae and Akr1b1tm1.1Kgab/Akr1b1tm1.1Kgab Akr1a1Gt(OST222400)Lex/Akr1a1Gt(OST222400)Lex bones (details)
Represented Alleles:
Akr1a1Gt(OST222400)Lex, aldo-keto reductase family 1, member A1; gene trap OST222400, Lexicon Genetics
Akr1b1tm1.1Kgab, aldo-keto reductase family 1 member B; targeted mutation 1.1, Kenneth H Gabbay
Gulotm1Mae, gulonolactone (L-) oxidase; targeted mutation 1, Nobuyo Maeda
Copyright: This image is from Gabbay KH, J Biol Chem 2010 Jun 18;285(25):19510-20 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:164548
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
MGI 6.24 		The Jackson Laboratory