Phenotype Images associated with this Gene

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Phenotype Images associated with this Gene

Symbol
Name
ID

Sgpp1
sphingosine-1-phosphate phosphatase 1
MGI:2135760

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	Caption: Sgpp2^tm1Rlp/Sgpp2^tm1Rlp mice showed normal skin appearance similar to wild-type mice, in contrast to severe ichtyosis in Sgpp1^{tm1(KOMP)Vlcg}/Sgpp1^{tm1(KOMP)Vlcg} mice (details) Represented Alleles: Sgpp1^{tm1(KOMP)Vlcg}, sphingosine-1-phosphate phosphatase 1; targeted mutation 1, Velocigene Sgpp1^{tm1(KOMP)Vlcg}, sphingosine-1-phosphate phosphatase 1; targeted mutation 1, Velocigene Sgpp2^tm1Rlp, sphingosine-1-phosphate phosphatase 2; targeted mutation 1, Richard L Proia Copyright: This image is from Taguchi Y, J Biol Chem 2016 Jun 3;291(23):12029-38 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:235035
	Caption: Sgpp1^{tm1(KOMP)Vlcg}/Sgpp1^{tm1(KOMP)Vlcg} pups exhibit focal desquamation and abnormal epidermal histology (details) Represented Alleles: Sgpp1^{tm1(KOMP)Vlcg}, sphingosine-1-phosphate phosphatase 1; targeted mutation 1, Velocigene Sgpp1^{tm1(KOMP)Vlcg}, sphingosine-1-phosphate phosphatase 1; targeted mutation 1, Velocigene Copyright: This image is from Allende ML, J Biol Chem 2013 Jun 21;288(25):18381-91 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:199597
	Caption: Abnormal skin in surviving Sgpp1^{tm1(KOMP)Vlcg}/Sgpp1^{tm1(KOMP)Vlcg} adult mice (details) Represented Alleles: Sgpp1^{tm1(KOMP)Vlcg}, sphingosine-1-phosphate phosphatase 1; targeted mutation 1, Velocigene Sgpp1^{tm1(KOMP)Vlcg}, sphingosine-1-phosphate phosphatase 1; targeted mutation 1, Velocigene Copyright: This image is from Allende ML, J Biol Chem 2013 Jun 21;288(25):18381-91 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:199597

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