Phenotype Images associated with this Gene

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Phenotype Images associated with this Gene

Symbol
Name
ID

Mob1a
MOB kinase activator 1A
MGI:2442631

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Click on allele symbol for full phenotype details.

	Caption: Tumorgenesis in Mob1a^tm1.2Asuz/Mob1a^tm1.2Asuz Mob1b^{Gt(CC0690)Wtsi}/Mob1b⁺ or Mob1a^tm1.2Asuz/Mob1a⁺ Mob1b^{Gt(CC0690)Wtsi}/Mob1b^{Gt(CC0690)Wtsi} mice (details) Represented Alleles: Mob1a^tm1.2Asuz, MOB kinase activator 1A; targeted mutation 1.2, Akira Suzuki Mob1b^{Gt(CC0690)Wtsi}, MOB kinase activator 1B; gene trap CC0690, Wellcome Trust Sanger Institute Copyright: This image is from Nishio M, J Clin Invest 2012 Dec 3;122(12):4505-18 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:193981
	Caption: Skin and hair abnormalities and large paws in tamoxifen treated Mob1a^tm1.1Asuz/Mob1a^tm1.1Asuz Tg(KRT14-cre/ERT)20Efu/0 Mob1b^{Gt(CC0690)Wtsi}/Mob1b^{Gt(CC0690)Wtsi} mice (details) Represented Alleles: Mob1a^tm1.1Asuz, MOB kinase activator 1A; targeted mutation 1.1, Akira Suzuki Mob1b^{Gt(CC0690)Wtsi}, MOB kinase activator 1B; gene trap CC0690, Wellcome Trust Sanger Institute Tg(KRT14-cre/ERT)20Efu, transgene insertion 20, Elaine Fuchs Tg(KRT14-cre/ERT)20Efu, transgene insertion 20, Elaine Fuchs Copyright: This image is from Nishio M, J Clin Invest 2012 Dec 3;122(12):4505-18 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:193981
	Caption: Increased proliferation, repressed apoptosis, and impaired contact inhibition and chromosome segregation in Mob1a^tm1.1Asuz/Mob1a^tm1.1Asuz Tg(KRT14-cre/ERT)20Efu/0 Mob1b^{Gt(CC0690)Wtsi}/Mob1b^{Gt(CC0690)Wtsi} keratinocytes (details) Represented Alleles: Mob1a^tm1.1Asuz, MOB kinase activator 1A; targeted mutation 1.1, Akira Suzuki Mob1b^{Gt(CC0690)Wtsi}, MOB kinase activator 1B; gene trap CC0690, Wellcome Trust Sanger Institute Tg(KRT14-cre/ERT)20Efu, transgene insertion 20, Elaine Fuchs Copyright: This image is from Nishio M, J Clin Invest 2012 Dec 3;122(12):4505-18 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:193981
	Caption: Skin cancer in Mob1a^tm1.2Asuz/Mob1a^tm1.2Asuz Mob1b^{Gt(CC0690)Wtsi}/Mob1b⁺ and Mob1a^tm1.2Asuz/Mob1a⁺ Mob1b^{Gt(CC0690)Wtsi}/Mob1b^{Gt(CC0690)Wtsi} mice (details) Represented Alleles: Mob1a^tm1.2Asuz, MOB kinase activator 1A; targeted mutation 1.2, Akira Suzuki Mob1b^{Gt(CC0690)Wtsi}, MOB kinase activator 1B; gene trap CC0690, Wellcome Trust Sanger Institute Copyright: This image is from Nishio M, J Clin Invest 2012 Dec 3;122(12):4505-18 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:193981
	Caption: Dental malocclusion, disorganized hair bundles, and increased trabeculae number in femoral bone of Mob1a^tm1.2Asuz/Mob1a⁺ Mob1b^{Gt(CC0690)Wtsi}/Mob1b^{Gt(CC0690)Wtsi} mice (details) Represented Alleles: Mob1a^tm1.2Asuz, MOB kinase activator 1A; targeted mutation 1.2, Akira Suzuki Mob1b^{Gt(CC0690)Wtsi}, MOB kinase activator 1B; gene trap CC0690, Wellcome Trust Sanger Institute Copyright: This image is from Nishio M, J Clin Invest 2012 Dec 3;122(12):4505-18 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:193981
	Caption: Hair follicle and interfollicular epidermis hyperplasia in tamoxifen treated Mob1a^tm1.1Asuz/Mob1a^tm1.1Asuz Tg(KRT14-cre/ERT)20Efu/0 Mob1b^{Gt(CC0690)Wtsi}/Mob1b^{Gt(CC0690)Wtsi} mice (details) Represented Alleles: Mob1a^tm1.1Asuz, MOB kinase activator 1A; targeted mutation 1.1, Akira Suzuki Mob1b^{Gt(CC0690)Wtsi}, MOB kinase activator 1B; gene trap CC0690, Wellcome Trust Sanger Institute Tg(KRT14-cre/ERT)20Efu, transgene insertion 20, Elaine Fuchs Copyright: This image is from Nishio M, J Clin Invest 2012 Dec 3;122(12):4505-18 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:193981

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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