Phenotype Images associated with this Gene

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Phenotype Images associated with this Gene

Symbol
Name
ID

Paxx
non-homologous end joining factor
MGI:2442831

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Click on allele symbol for full phenotype details.

	Caption: Small body size, absence of thymus, and small spleen in Paxx^em1Spj/Paxx^em1Spj Nhej1^tm1Fwa/Nhej1^tm1Fwa mice (details) Represented Alleles: Nhej1^tm1Fwa, non-homologous end joining factor 1; targeted mutation 1, Frederick W Alt Paxx^em1Spj, non-homologous end joining factor; endonuclease-mediated mutation 1, Stephen P Jackson Copyright: This image is from Balmus G, Genes Dev 2016 Oct 1;30(19):2152-2157, and is displayed with the permission of Cold Spring Harbor Laboratory Press, who owns the Copyright. J:236776
	Caption: Small size, much smaller spleens and drastic involution of the thymus in Paxx^em1Spj/Paxx^em1Spj Nhej1^tm1Fwa/Nhej1^tm1Fwa mice (details) Represented Alleles: Nhej1^tm1Fwa, non-homologous end joining factor 1; targeted mutation 1, Frederick W Alt Paxx^em1Spj, non-homologous end joining factor; endonuclease-mediated mutation 1, Stephen P Jackson Copyright: This image is from Balmus G, Genes Dev 2016 Oct 1;30(19):2152-2157, and is displayed with the permission of Cold Spring Harbor Laboratory Press, who owns the Copyright. J:236776
	Caption: Increased genomic instability and apoptosis in the central nervous system of Paxx^em1Spj/Paxx^em1Spj Nhej1^tm1Fwa/Nhej1^tm1Fwa embryos (details) Represented Alleles: Nhej1^tm1Fwa, non-homologous end joining factor 1; targeted mutation 1, Frederick W Alt Paxx^em1Spj, non-homologous end joining factor; endonuclease-mediated mutation 1, Stephen P Jackson Copyright: This image is from Balmus G, Genes Dev 2016 Oct 1;30(19):2152-2157, and is displayed with the permission of Cold Spring Harbor Laboratory Press, who owns the Copyright. J:236776
	Caption: Small size of 5-day old Paxx^em1Spj/Paxx^em1Spj Nhej1^tm1Fwa/Nhej1^tm1Fwa (arow) mouse (details) Represented Alleles: Nhej1^tm1Fwa, non-homologous end joining factor 1; targeted mutation 1, Frederick W Alt Paxx^em1Spj, non-homologous end joining factor; endonuclease-mediated mutation 1, Stephen P Jackson Copyright: This image is from Balmus G, Genes Dev 2016 Oct 1;30(19):2152-2157, and is displayed with the permission of Cold Spring Harbor Laboratory Press, who owns the Copyright. J:236776

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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