About   Help   FAQ
Phenotype Images associated with this Gene
Symbol
Name
ID 		Pik3c3
phosphatidylinositol 3-kinase catalytic subunit type 3
MGI:2445019


8 phenotype image(s) for Pik3c3 alleles
Showing image(s) 1 to 8
Click on thumbnail to view full size image with links to phenotype annotations.
Click on allele symbol for full phenotype details.

Caption: Cataracts and impaired differentiation of secondary lens fiber cells in Pik3c3tm1Tssk/Pik3c3tm1Tssk Tg(Cryaa-cre)10Mlr/0 mice (details)
Represented Alleles:
Pik3c3tm1Tssk, phosphatidylinositol 3-kinase catalytic subunit type 3; targeted mutation 1, Takehiko Sasaki
Tg(Cryaa-cre)10Mlr, transgene insertion 10, Mike Robinson
Copyright: This image is from Morishita H, J Biol Chem 2013 Apr 19;288(16):11436-47 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:198392
Caption: Accumulation of vacuoles in Pik3c3tm1Tssk/Pik3c3tm1Tssk Tg(Cryaa-cre)10Mlr/0 secondary lens fiber cells (details)
Represented Alleles:
Pik3c3tm1Tssk, phosphatidylinositol 3-kinase catalytic subunit type 3; targeted mutation 1, Takehiko Sasaki
Tg(Cryaa-cre)10Mlr, transgene insertion 10, Mike Robinson
Copyright: This image is from Morishita H, J Biol Chem 2013 Apr 19;288(16):11436-47 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:198392
Caption: Pik3c3tm1c(EUCOMM)Wtsi/Pik3c3tm1c(EUCOMM)Wtsi MEFs transduced with cre-expressing adenovirus exhibit large translucent vacuoles (details)
Represented Alleles:
Pik3c3tm1c(EUCOMM)Wtsi, phosphatidylinositol 3-kinase catalytic subunit type 3; targeted mutation 1c, Wellcome Trust Sanger Institute
Copyright: This image is from Jaber N, Proc Natl Acad Sci U S A 2012 Feb 7;109(6):2003-8. Copyright 2012 National Academy of Sciences, U.S.A. J:182628
Caption: Hepatomegaly in Pik3c3tm1c(EUCOMM)Wtsi/Pik3c3tm1c(EUCOMM)Wtsi Speer6-ps1Tg(Alb-cre)21Mgn/0 mice (details)
Represented Alleles:
Pik3c3tm1c(EUCOMM)Wtsi, phosphatidylinositol 3-kinase catalytic subunit type 3; targeted mutation 1c, Wellcome Trust Sanger Institute
Speer6-ps1Tg(Alb-cre)21Mgn, spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1; transgene insertion 21, Mark A Magnuson
Copyright: This image is from Jaber N, Proc Natl Acad Sci U S A 2012 Feb 7;109(6):2003-8. Copyright 2012 National Academy of Sciences, U.S.A. J:182628
Caption: Liver steatosis in Pik3c3tm1c(EUCOMM)Wtsi/Pik3c3tm1c(EUCOMM)Wtsi Speer6-ps1Tg(Alb-cre)21Mgn/0 mice (details)
Represented Alleles:
Pik3c3tm1c(EUCOMM)Wtsi, phosphatidylinositol 3-kinase catalytic subunit type 3; targeted mutation 1c, Wellcome Trust Sanger Institute
Speer6-ps1Tg(Alb-cre)21Mgn, spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1; transgene insertion 21, Mark A Magnuson
Copyright: This image is from Jaber N, Proc Natl Acad Sci U S A 2012 Feb 7;109(6):2003-8. Copyright 2012 National Academy of Sciences, U.S.A. J:182628
Caption: Hepatocyte abnormalities in Pik3c3tm1c(EUCOMM)Wtsi/Pik3c3tm1c(EUCOMM)Wtsi Speer6-ps1Tg(Alb-cre)21Mgn/0 mice (details)
Represented Alleles:
Pik3c3tm1c(EUCOMM)Wtsi, phosphatidylinositol 3-kinase catalytic subunit type 3; targeted mutation 1c, Wellcome Trust Sanger Institute
Speer6-ps1Tg(Alb-cre)21Mgn, spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1; transgene insertion 21, Mark A Magnuson
Copyright: This image is from Jaber N, Proc Natl Acad Sci U S A 2012 Feb 7;109(6):2003-8. Copyright 2012 National Academy of Sciences, U.S.A. J:182628
Caption: Cardiac dysfunction in Pik3c3tm1c(EUCOMM)Wtsi/Pik3c3tm1c(EUCOMM)Wtsi Tg(Ckmm-cre)5Khn/0 mice (details)
Represented Alleles:
Pik3c3tm1c(EUCOMM)Wtsi, phosphatidylinositol 3-kinase catalytic subunit type 3; targeted mutation 1c, Wellcome Trust Sanger Institute
Tg(Ckmm-cre)5Khn, transgene insertion 5, C Ronald Kahn
Copyright: This image is from Jaber N, Proc Natl Acad Sci U S A 2012 Feb 7;109(6):2003-8. Copyright 2012 National Academy of Sciences, U.S.A. J:182628
Caption: Pik3c3tm1c(EUCOMM)Wtsi/Pik3c3tm1c(EUCOMM)Wtsi Speer6-ps1Tg(Alb-cre)21Mgn/0 livers contain multiple large empty vacuoles (details)
Represented Alleles:
Pik3c3tm1c(EUCOMM)Wtsi, phosphatidylinositol 3-kinase catalytic subunit type 3; targeted mutation 1c, Wellcome Trust Sanger Institute
Speer6-ps1Tg(Alb-cre)21Mgn, spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1; transgene insertion 21, Mark A Magnuson
Copyright: This image is from Jaber N, Proc Natl Acad Sci U S A 2012 Feb 7;109(6):2003-8. Copyright 2012 National Academy of Sciences, U.S.A. J:182628
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory