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Phenotype Images associated with this Gene
Symbol
Name
ID 		Pik3c3
phosphatidylinositol 3-kinase catalytic subunit type 3
MGI:2445019


8 phenotype image(s) for Pik3c3 alleles
Showing image(s) 1 to 8
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Click on allele symbol for full phenotype details.

Caption: Cataracts and impaired differentiation of secondary lens fiber cells in Pik3c3tm1Tssk/Pik3c3tm1Tssk Tg(Cryaa-cre)10Mlr/0 mice (details)
Represented Alleles:
Pik3c3tm1Tssk, phosphatidylinositol 3-kinase catalytic subunit type 3; targeted mutation 1, Takehiko Sasaki
Tg(Cryaa-cre)10Mlr, transgene insertion 10, Mike Robinson
Copyright: This image is from Morishita H, J Biol Chem 2013 Apr 19;288(16):11436-47 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:198392
Caption: Accumulation of vacuoles in Pik3c3tm1Tssk/Pik3c3tm1Tssk Tg(Cryaa-cre)10Mlr/0 secondary lens fiber cells (details)
Represented Alleles:
Pik3c3tm1Tssk, phosphatidylinositol 3-kinase catalytic subunit type 3; targeted mutation 1, Takehiko Sasaki
Tg(Cryaa-cre)10Mlr, transgene insertion 10, Mike Robinson
Copyright: This image is from Morishita H, J Biol Chem 2013 Apr 19;288(16):11436-47 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:198392
Caption: Pik3c3tm1c(EUCOMM)Wtsi/Pik3c3tm1c(EUCOMM)Wtsi MEFs transduced with cre-expressing adenovirus exhibit large translucent vacuoles (details)
Represented Alleles:
Pik3c3tm1c(EUCOMM)Wtsi, phosphatidylinositol 3-kinase catalytic subunit type 3; targeted mutation 1c, Wellcome Trust Sanger Institute
Copyright: This image is from Jaber N, Proc Natl Acad Sci U S A 2012 Feb 7;109(6):2003-8. Copyright 2012 National Academy of Sciences, U.S.A. J:182628
Caption: Hepatomegaly in Pik3c3tm1c(EUCOMM)Wtsi/Pik3c3tm1c(EUCOMM)Wtsi Speer6-ps1Tg(Alb-cre)21Mgn/0 mice (details)
Represented Alleles:
Pik3c3tm1c(EUCOMM)Wtsi, phosphatidylinositol 3-kinase catalytic subunit type 3; targeted mutation 1c, Wellcome Trust Sanger Institute
Speer6-ps1Tg(Alb-cre)21Mgn, spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1; transgene insertion 21, Mark A Magnuson
Copyright: This image is from Jaber N, Proc Natl Acad Sci U S A 2012 Feb 7;109(6):2003-8. Copyright 2012 National Academy of Sciences, U.S.A. J:182628
Caption: Liver steatosis in Pik3c3tm1c(EUCOMM)Wtsi/Pik3c3tm1c(EUCOMM)Wtsi Speer6-ps1Tg(Alb-cre)21Mgn/0 mice (details)
Represented Alleles:
Pik3c3tm1c(EUCOMM)Wtsi, phosphatidylinositol 3-kinase catalytic subunit type 3; targeted mutation 1c, Wellcome Trust Sanger Institute
Speer6-ps1Tg(Alb-cre)21Mgn, spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1; transgene insertion 21, Mark A Magnuson
Copyright: This image is from Jaber N, Proc Natl Acad Sci U S A 2012 Feb 7;109(6):2003-8. Copyright 2012 National Academy of Sciences, U.S.A. J:182628
Caption: Hepatocyte abnormalities in Pik3c3tm1c(EUCOMM)Wtsi/Pik3c3tm1c(EUCOMM)Wtsi Speer6-ps1Tg(Alb-cre)21Mgn/0 mice (details)
Represented Alleles:
Pik3c3tm1c(EUCOMM)Wtsi, phosphatidylinositol 3-kinase catalytic subunit type 3; targeted mutation 1c, Wellcome Trust Sanger Institute
Speer6-ps1Tg(Alb-cre)21Mgn, spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1; transgene insertion 21, Mark A Magnuson
Copyright: This image is from Jaber N, Proc Natl Acad Sci U S A 2012 Feb 7;109(6):2003-8. Copyright 2012 National Academy of Sciences, U.S.A. J:182628
Caption: Cardiac dysfunction in Pik3c3tm1c(EUCOMM)Wtsi/Pik3c3tm1c(EUCOMM)Wtsi Tg(Ckmm-cre)5Khn/0 mice (details)
Represented Alleles:
Pik3c3tm1c(EUCOMM)Wtsi, phosphatidylinositol 3-kinase catalytic subunit type 3; targeted mutation 1c, Wellcome Trust Sanger Institute
Tg(Ckmm-cre)5Khn, transgene insertion 5, C Ronald Kahn
Copyright: This image is from Jaber N, Proc Natl Acad Sci U S A 2012 Feb 7;109(6):2003-8. Copyright 2012 National Academy of Sciences, U.S.A. J:182628
Caption: Pik3c3tm1c(EUCOMM)Wtsi/Pik3c3tm1c(EUCOMM)Wtsi Speer6-ps1Tg(Alb-cre)21Mgn/0 livers contain multiple large empty vacuoles (details)
Represented Alleles:
Pik3c3tm1c(EUCOMM)Wtsi, phosphatidylinositol 3-kinase catalytic subunit type 3; targeted mutation 1c, Wellcome Trust Sanger Institute
Speer6-ps1Tg(Alb-cre)21Mgn, spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1; transgene insertion 21, Mark A Magnuson
Copyright: This image is from Jaber N, Proc Natl Acad Sci U S A 2012 Feb 7;109(6):2003-8. Copyright 2012 National Academy of Sciences, U.S.A. J:182628
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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07/05/2024
MGI 6.24 		The Jackson Laboratory