Phenotype Images associated with this Gene

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Phenotype Images associated with this Gene

Symbol
Name
ID

Megf8
multiple EGF-like-domains 8
MGI:2446294

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Click on allele symbol for full phenotype details.

	Caption: Mutant 1702-007-1 (E16.5) exhibits dextrocardia and displaced outflow tracts, later diagnosed as Taussig-Bing type double outlet right ventricle (DORV) by ECM histopathology. (details) Represented Alleles: b2b1702Clo, Mutant line 1702, Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 1702 Cecilia Lo Megf8^b2b1702.2Clo, multiple EGF-like-domains 8; Bench to Bassinet Program (B2B/CVDC), mutation 1702, subline 2 Cecilia Lo Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
	Caption: EFIC Summary (details) Represented Alleles: b2b1702Clo, Mutant line 1702, Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 1702 Cecilia Lo Megf8^b2b1702.2Clo, multiple EGF-like-domains 8; Bench to Bassinet Program (B2B/CVDC), mutation 1702, subline 2 Cecilia Lo Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
	Caption: Serial 2D EFIC image stack in the coronal plane of 1702-007-1 (E16.5) reveals dextrocardia, Taussig-Bing type double outlet right ventricle, and atrioventricular septal defect (AVSD) {I,L,L]. Click thumbnail to play movie. (details) Represented Alleles: b2b1702Clo, Mutant line 1702, Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 1702 Cecilia Lo Megf8^b2b1702.2Clo, multiple EGF-like-domains 8; Bench to Bassinet Program (B2B/CVDC), mutation 1702, subline 2 Cecilia Lo Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
	Caption: Mutant 1702-007-1 (E16.5) presents with dextrogastria and a hypoplastic spleen. (details) Represented Alleles: b2b1702Clo, Mutant line 1702, Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 1702 Cecilia Lo Megf8^b2b1702.2Clo, multiple EGF-like-domains 8; Bench to Bassinet Program (B2B/CVDC), mutation 1702, subline 2 Cecilia Lo Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
	Caption: Mutant 1702-007-1 (E16.5) shows a hypoplastic thymus. (details) Represented Alleles: b2b1702Clo, Mutant line 1702, Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 1702 Cecilia Lo Megf8^b2b1702.2Clo, multiple EGF-like-domains 8; Bench to Bassinet Program (B2B/CVDC), mutation 1702, subline 2 Cecilia Lo Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
	Caption: Mutant 1702-007-1 (E15.5) exhibits petechiae, left eye anophthalmia, short snout, micrognathia, and is runted. (details) Represented Alleles: b2b1702Clo, Mutant line 1702, Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 1702 Cecilia Lo Megf8^b2b1702.2Clo, multiple EGF-like-domains 8; Bench to Bassinet Program (B2B/CVDC), mutation 1702, subline 2 Cecilia Lo Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
	Caption: Mutant 1702-007-1 (E15.5) exhibits right eye microphthalmia. (details) Represented Alleles: b2b1702Clo, Mutant line 1702, Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 1702 Cecilia Lo Megf8^b2b1702.2Clo, multiple EGF-like-domains 8; Bench to Bassinet Program (B2B/CVDC), mutation 1702, subline 2 Cecilia Lo Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
	Caption: Heterotaxia in Megf8^hlb611/Megf8^hlb611 embryos as indicated by altered expression of left determinant genes (details) Represented Alleles: Megf8^hlb611, multiple EGF-like-domains 8; heart, lung and blood 611 Copyright: This image is from Zhang Z, Proc Natl Acad Sci U S A 2009 Mar 3;106(9):3219-24. Copyright 2009 National Academy of Sciences, U.S.A. J:146805
	Caption: Left-right asymmetric defects in Megf8^hlb611/Megf8^hlb611 embryos (details) Represented Alleles: Megf8^hlb611, multiple EGF-like-domains 8; heart, lung and blood 611 Copyright: This image is from Zhang Z, Proc Natl Acad Sci U S A 2009 Mar 3;106(9):3219-24. Copyright 2009 National Academy of Sciences, U.S.A. J:146805

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