Phenotype Images associated with this Gene

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Phenotype Images associated with this Gene

Symbol
Name
ID

Lrrc8a
leucine rich repeat containing 8A VRAC subunit A
MGI:2652847

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	Caption: Growth retardation, epidermal hyperkeratosis, thin skeletal muscle bundles, vacuolated renal tubular cells, and absence of ovarian corpora lutea in Lrrc8a^tm1.1Geha/Lrrc8a^tm1.1Geha mice (details) Represented Alleles: Lrrc8a^tm1.1Geha, leucine rich repeat containing 8A VRAC subunit A; targeted mutation 1.1, Raif S Geha Copyright: This image is from Kumar L, J Exp Med 2014 May 5;211(5):929-42, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:211308
	Caption: Lrrc8a^tm1.1Geha/Lrrc8a^tm1.1Geha mice have small spleens with well-preserved architecture (details) Represented Alleles: Lrrc8a^tm1.1Geha, leucine rich repeat containing 8A VRAC subunit A; targeted mutation 1.1, Raif S Geha Copyright: This image is from Kumar L, J Exp Med 2014 May 5;211(5):929-42, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:211308
	Caption: Decreased thymic cellularity and impaired thymocyte viability in Lrrc8a^tm1.1Geha/Lrrc8a^tm1.1Geha mice (details) Represented Alleles: Lrrc8a^tm1.1Geha, leucine rich repeat containing 8A VRAC subunit A; targeted mutation 1.1, Raif S Geha Copyright: This image is from Kumar L, J Exp Med 2014 May 5;211(5):929-42, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:211308

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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