Symbol Name ID |
b2b2696Clo
Mutant line 2696 MGI:5620178 |
Caption: Mutant (E14.5) shows dextrocardia with abnormal outflow tract arrangement with DORV as seen by ECM hisopathology.
(details)
Represented Alleles:
b2b2696.1Clo,
Mutant line 2696.1; Bench to Bassinet Program (B2B/CVDC), mutation 2696, subline 1 Cecilia Lo
b2b2696Clo,
Mutant line 2696; Bench to Bassinet Program (B2B/CVDC), mutation 2696 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
|
|
Caption: EFIC Summary
(details)
Represented Alleles:
b2b2696.1Clo,
Mutant line 2696.1; Bench to Bassinet Program (B2B/CVDC), mutation 2696, subline 1 Cecilia Lo
b2b2696Clo,
Mutant line 2696; Bench to Bassinet Program (B2B/CVDC), mutation 2696 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
|
|
Caption: Serial 2D ECM image stack of (ED14.5) in the coronal plane reveals dextracardia {A,D,D} with DORV, AVSD, muscular VSD, right atrial isomerism with absent coronary sinus, intracardiac TAPVR, dual IVC, left aortic arch, delayed myocardial compaction (or myocardial non-compaction), and left lung isomerism.
Click thumbnail to play movie. (details) Represented Alleles:
b2b2696.1Clo,
Mutant line 2696.1; Bench to Bassinet Program (B2B/CVDC), mutation 2696, subline 1 Cecilia Lo
b2b2696Clo,
Mutant line 2696; Bench to Bassinet Program (B2B/CVDC), mutation 2696 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
|
|
Caption: Mutant (E14.5) presents with a right-sided pancreas, asplenia, left-sided stomach and gut malrotation.
(details)
Represented Alleles:
b2b2696.1Clo,
Mutant line 2696.1; Bench to Bassinet Program (B2B/CVDC), mutation 2696, subline 1 Cecilia Lo
b2b2696Clo,
Mutant line 2696; Bench to Bassinet Program (B2B/CVDC), mutation 2696 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors
J:175213
|
|
Caption: Mutant exhibits a right aortic arch which was confirmed by ECM imaging.
(details)
Represented Alleles:
b2b2696.2Clo,
Mutant line 2696.2; Bench to Bassinet Program (B2B/CVDC), mutation 2696, subline 2 Cecilia Lo
b2b2696Clo,
Mutant line 2696; Bench to Bassinet Program (B2B/CVDC), mutation 2696 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
|
|
Caption: EFIC Summary
(details)
Represented Alleles:
b2b2696.2Clo,
Mutant line 2696.2; Bench to Bassinet Program (B2B/CVDC), mutation 2696, subline 2 Cecilia Lo
b2b2696Clo,
Mutant line 2696; Bench to Bassinet Program (B2B/CVDC), mutation 2696 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
|
|
Caption: Serial 2D ECM image stack in the coronal plane of mutant reveals right aortic arch, coronary artery fistula, and aberrant left subclavian artery forming incomplete vascular ring.
Click thumbnail to play movie. (details) Represented Alleles:
b2b2696.2Clo,
Mutant line 2696.2; Bench to Bassinet Program (B2B/CVDC), mutation 2696, subline 2 Cecilia Lo
b2b2696Clo,
Mutant line 2696; Bench to Bassinet Program (B2B/CVDC), mutation 2696 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
|
|
Caption: Mutant exhibits craniofacial defects which include craniofacial hypoplasia, severe micrognathia/agnathia, bilateral anopthalmia, and low-set ears.
(details)
Represented Alleles:
b2b2696.2Clo,
Mutant line 2696.2; Bench to Bassinet Program (B2B/CVDC), mutation 2696, subline 2 Cecilia Lo
b2b2696Clo,
Mutant line 2696; Bench to Bassinet Program (B2B/CVDC), mutation 2696 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
|
|
Caption: Mutant presents with apparent left ventricular hypertrophy which was confirmed by ECM histopatholog
(details)
Represented Alleles:
b2b2696.2Clo,
Mutant line 2696.2; Bench to Bassinet Program (B2B/CVDC), mutation 2696, subline 2 Cecilia Lo
b2b2696Clo,
Mutant line 2696; Bench to Bassinet Program (B2B/CVDC), mutation 2696 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
|
|
Caption: EFIC Summary
(details)
Represented Alleles:
b2b2696.2Clo,
Mutant line 2696.2; Bench to Bassinet Program (B2B/CVDC), mutation 2696, subline 2 Cecilia Lo
b2b2696Clo,
Mutant line 2696; Bench to Bassinet Program (B2B/CVDC), mutation 2696 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 12/10/2024 MGI 6.24 |
|
|