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Phenotype Images associated with this Gene
Symbol
Name
ID 		b2b2966Clo
Mutant line 2966 Cecilia Lo
MGI:5646288


30 phenotype image(s) for b2b2966Clo alleles
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Caption: Mutant 2966-005-2 (E15.5) displays heterotaxy with mesocardia and left lung isomerism. (details)
Represented Alleles:
b2b2966Clo, Mutant line 2966 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 2966 Cecilia Lo
Lama5b2b2966.1Clo, laminin, alpha 5; Bench to Bassinet Program (B2B/CVDC), mutation 2966, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 2966-005-2 (E15.5) exhibits abnormal liver lobation. (details)
Represented Alleles:
b2b2966Clo, Mutant line 2966 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 2966 Cecilia Lo
Lama5b2b2966.1Clo, laminin, alpha 5; Bench to Bassinet Program (B2B/CVDC), mutation 2966, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: 2966-005-2 mutant exhibits mesocardia, hypoplastic right ventrical, perimembrnous and muscular VSDs, aberrant right subclavian artery forming incomplete vascular ring, left lung isomerism as seen by episcopic confocal microscopy. (details)
Represented Alleles:
b2b2966Clo, Mutant line 2966 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 2966 Cecilia Lo
Lama5b2b2966.1Clo, laminin, alpha 5; Bench to Bassinet Program (B2B/CVDC), mutation 2966, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Serial 2D episcopic confocal microscopy image stack in the coronal plane of 2966-005-2 (E15.5) reveals mesocardia, perimembranous ventricular septal defect (pmVSD), muscular ventricular septal defect (mVSD), aberrant right subclavian artery forming incomplete vascular ring, and left lung isomerism.
Click thumbnail to play movie. (details)
Represented Alleles:
b2b2966Clo, Mutant line 2966 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 2966 Cecilia Lo
Lama5b2b2966.1Clo, laminin, alpha 5; Bench to Bassinet Program (B2B/CVDC), mutation 2966, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 2966-005-2 (E15.5) presents with exencephaly, anophthalmia, agnathia, low-set ears, and is runted. (details)
Represented Alleles:
b2b2966Clo, Mutant line 2966 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 2966 Cecilia Lo
Lama5b2b2966.1Clo, laminin, alpha 5; Bench to Bassinet Program (B2B/CVDC), mutation 2966, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 2966-005-2 (E15.5) exhibits a curly tail and syndactyly/webbed feet. (details)
Represented Alleles:
b2b2966Clo, Mutant line 2966 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 2966 Cecilia Lo
Lama5b2b2966.1Clo, laminin, alpha 5; Bench to Bassinet Program (B2B/CVDC), mutation 2966, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 2966-005-2 (E15.5) presents with only a left thymus gland which is hypoplastic. (details)
Represented Alleles:
b2b2966Clo, Mutant line 2966 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 2966 Cecilia Lo
Lama5b2b2966.1Clo, laminin, alpha 5; Bench to Bassinet Program (B2B/CVDC), mutation 2966, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 2966-005-1 (E15.5) shows parallel outflow tracts which is diagnosed by episcopic confocal histopathology as overriding aorta. (details)
Represented Alleles:
b2b2966Clo, Mutant line 2966 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 2966 Cecilia Lo
Lama5b2b2966.1Clo, laminin, alpha 5; Bench to Bassinet Program (B2B/CVDC), mutation 2966, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: 2966-005-1 mutant exhibits overriding aorta (Tetralogy of Fallot type), perimembranous ventricular septal disorder, small pulmonary artery, and aberrant right subclavian artery forming incomplete vascular ring as seen by episcopic confocal microscopy. (details)
Represented Alleles:
b2b2966Clo, Mutant line 2966 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 2966 Cecilia Lo
Lama5b2b2966.1Clo, laminin, alpha 5; Bench to Bassinet Program (B2B/CVDC), mutation 2966, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Serial 2D episcopic confocal microscopy image stack in the coronal plane of 2966-005-1 (E15.5) reveals overriding aorta (tetrology of fallot type), perimembranous ventricular septal defect (pmVSD), small pulmonary artery (PA) , and aberrant right subclavian artery forming an incomplete vascular ring.
Click thumbnail to play movie. (details)
Represented Alleles:
b2b2966Clo, Mutant line 2966 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 2966 Cecilia Lo
Lama5b2b2966.1Clo, laminin, alpha 5; Bench to Bassinet Program (B2B/CVDC), mutation 2966, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
MGI 6.24 		The Jackson Laboratory