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Phenotype Images associated with this Gene
Symbol
Name
ID 		b2b3077.2Clo
Mutant line 3077, subline 2 Cecilia Lo
MGI:5646610


10 phenotype image(s) for b2b3077.2Clo alleles
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Caption: Mutant 3077-006-4 (E15.5) exhibits aortic atresia with accessory anterior lung lobes, hypoplastic left atrium, and thickened left ventricle wall. This is diagnosed as aortic atresia, left venricle hypertrophy, and hypoplastic left heart syndrome (HLHS) spectrum heart by ECM histopathology. (details)
Represented Alleles:
b2b3077.2Clo, Mutant line 3077, subline 2 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 2 Cecilia Lo
b2b3077Clo, Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: EFIC Summary (details)
Represented Alleles:
b2b3077.2Clo, Mutant line 3077, subline 2 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 2 Cecilia Lo
b2b3077Clo, Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Serial 2D ECM image stack of 3077-006-4 (E15.5) in the coronal plane reveals hypoplastic left heart syndrome with aortic atresia, mitral valve stenosis, and muscle bound hypoplastic left ventricle. Also noted was abnormal acccessory anterior lung lobes.
Click thumbnail to play movie. (details)
Represented Alleles:
b2b3077.2Clo, Mutant line 3077, subline 2 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 2 Cecilia Lo
b2b3077Clo, Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: 3D ECM reconstruction of 3077-006-4 shows accessory anterior lung lobes positioned above the atria.
Click thumbnail to play movie. (details)
Represented Alleles:
b2b3077.2Clo, Mutant line 3077, subline 2 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 2 Cecilia Lo
b2b3077Clo, Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 3077-006-4 (E15.5) presents with hydrops, short snout, micrognathia, short limbs, clubbed feet, syndactyly, and short tail. (details)
Represented Alleles:
b2b3077.2Clo, Mutant line 3077, subline 2 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 2 Cecilia Lo
b2b3077Clo, Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 3077-006-4 (E15.5) presents with a cleft lip. (details)
Represented Alleles:
b2b3077.2Clo, Mutant line 3077, subline 2 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 2 Cecilia Lo
b2b3077Clo, Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 3077-006-4 (E15.5) exhibits a cleft palate. (details)
Represented Alleles:
b2b3077.2Clo, Mutant line 3077, subline 2 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 2 Cecilia Lo
b2b3077Clo, Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 3077-006-4 (E15.5) shows a short gut. (details)
Represented Alleles:
b2b3077.2Clo, Mutant line 3077, subline 2 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 2 Cecilia Lo
b2b3077Clo, Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 3077-006-4 (E15.5) exhibits abnormally placed adrenal glands and cystic kidneys, later confirmed showing a few glomerular cysts by histopathology. (details)
Represented Alleles:
b2b3077.2Clo, Mutant line 3077, subline 2 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 2 Cecilia Lo
b2b3077Clo, Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 3077-006-4 (E15.5) shows some glomerular cysts. (details)
Represented Alleles:
b2b3077.2Clo, Mutant line 3077, subline 2 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 2 Cecilia Lo
b2b3077Clo, Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/29/2024
MGI 6.24 		The Jackson Laboratory