Phenotype Images associated with this Gene

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Phenotype Images associated with this Gene

Symbol
Name
ID

App
amyloid beta precursor protein
MGI:88059

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Click on allele symbol for full phenotype details.

	Caption: Beta-amyloid plaques in Tg(APPswe,PSEN1dE9)85Dbo/0 mice and neurofibrillary tangles in Mapt^tm1(EGFP)Klt/Mapt^tm1(EGFP)Klt Tg(MAPT)8cPdav/0 mice (details) Represented Alleles: Mapt^tm1(EGFP)Klt, microtubule-associated protein tau; targeted mutation 1, Kerry Lee Tucker Tg(APPswe,PSEN1dE9)85Dbo, transgene insertion 85, David R Borchelt Tg(MAPT)8cPdav, transgene insertion 8c, Peter Davies Copyright: This image is from Phillips M, PLoS One 2011;6(5):e19567, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:172426
	Caption: Amyloid beta deposits in App^tm3.1Zhe/App^tm3.1Zhe Psen1^tm1Mpm/Psen1^tm1Mpm mice (details) Represented Alleles: App^tm3.1Zhe, amyloid beta precursor protein; targeted mutation 3.1, Hui Zheng Psen1^tm1Mpm, presenilin 1; targeted mutation 1, Mark P Mattson Copyright: This image is from Li H, J Biol Chem 2010 Oct 1;285(40):30598-605 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:166379
	Caption: Neuromuscular synapse defects in App^tm3.1Zhe/App^tm3.1Zhe Aplp2^tm1Dbo/Aplp2^tm1Dbo mice (details) Represented Alleles: Aplp2^tm1Dbo, amyloid beta precursor-like protein 2; targeted mutation 1, David R Borchelt App^tm3.1Zhe, amyloid beta precursor protein; targeted mutation 3.1, Hui Zheng Copyright: This image is from Li H, J Biol Chem 2010 Oct 1;285(40):30598-605 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:166379

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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