Phenotype Images associated with this Gene

Symbol
Name
ID

Hlcs
holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase)
MGI:894646

Click on thumbnail to view full size image with links to phenotype annotations.
Click on allele symbol for full phenotype details.

Caption: Hlcs^em1(IMPC)J/Hlcs^em1(IMPC)J mice exhibit embryonic lethality. Embryos are recovered at E7.5 but arrest prior to gastrulation and no embryos are seen at E9.5. Embryos are smaller and form a rudimentary egg cylinder but no primitive streak or gastrulation are seen at E7.5. (details)

Represented Alleles:

Hlcs^em1(IMPC)J, holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase); endonuclease-mediated mutation 1, Jackson

Copyright: This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Jesse Mager at jmager@umass.edu J:279207

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24