Phenotype Images associated with this Gene

Symbol
Name
ID

Hmgcl
3-hydroxy-3-methylglutaryl-Coenzyme A lyase
MGI:96158

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Caption: The leucine metabolite 2-ketoisocaproate induces liver steatosis in Hmgcl^tm2Gam/Hmgcl^tm2Gam Speer6-ps1^{Tg(Alb-cre)21Mgn}/0 mice (details)

Represented Alleles:

Hmgcl^tm2Gam, 3-hydroxy-3-methylglutaryl-Coenzyme A lyase; targeted mutation 2, Grant A Mitchell

Speer6-ps1^{Tg(Alb-cre)21Mgn}, spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1; transgene insertion 21, Mark A Magnuson

Copyright: This image is from Gauthier N, PLoS One 2013;8(7):e60581, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:204294

Caption: Abnormalities of mitochondrial ultrastructure in Hmgcl^tm2Gam/Hmgcl^tm2Gam Speer6-ps1^{Tg(Alb-cre)21Mgn}/0 hepatocytes (details)

Represented Alleles:

Hmgcl^tm2Gam, 3-hydroxy-3-methylglutaryl-Coenzyme A lyase; targeted mutation 2, Grant A Mitchell

Speer6-ps1^{Tg(Alb-cre)21Mgn}, spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1; transgene insertion 21, Mark A Magnuson

Copyright: This image is from Gauthier N, PLoS One 2013;8(7):e60581, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:204294

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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