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Phenotype Images associated with this Gene
Symbol
Name
ID
Lyn
LYN proto-oncogene, Src family tyrosine kinase
MGI:96892


3 phenotype image(s) for Lyn alleles
Showing image(s) 1 to 3

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Click on allele symbol for full phenotype details.

Caption: Lupus-like autoimmune disease in Lyntm1Sor/Lyntm1Sor and Lyntm1.1Calo/Lyntm1.1Calo Top2aGt(PST14568)Mfgc/0 mice (details)
Represented Alleles:
Lyntm1.1Calo, LYN proto-oncogene, Src family tyrosine kinase; targeted mutation 1.1 Clifford A Lowell
Lyntm1Sor, LYN proto-oncogene, Src family tyrosine kinase; targeted mutation 1, Philippe Soriano
Tg(Itgax-cre)1-1Reiz, transgene insertion 1-1, Boris Reizis
Copyright: This image is from Lamagna C, Proc Natl Acad Sci U S A 2013 Aug 27;110(35):E3311-20. Copyright 2013 National Academy of Sciences, U.S.A. J:200745
Caption: By 8 months, severe leukocyte infiltration is seen in the lungs, liver and skin of Lyntm1Sor/Lyntm1Sor mice but not Lyntm1.1Calo/Lyntm1.1Calo Tg(Itgax-cre)1-1Reiz/0 mice (details)
Represented Alleles:
Lyntm1.1Calo, LYN proto-oncogene, Src family tyrosine kinase; targeted mutation 1.1 Clifford A Lowell
Lyntm1Sor, LYN proto-oncogene, Src family tyrosine kinase; targeted mutation 1, Philippe Soriano
Tg(Itgax-cre)1-1Reiz, transgene insertion 1-1, Boris Reizis
Copyright: This image is from Lamagna C, Proc Natl Acad Sci U S A 2013 Aug 27;110(35):E3311-20. Copyright 2013 National Academy of Sciences, U.S.A. J:200745
Caption: Splenomegaly and lymphadenopathy in Lyntm1Sor/Lyntm1Sor and Lyntm1.1Calo/Lyntm1.1Calo Tg(Itgax-cre)1-1Reiz/0 mice (details)
Represented Alleles:
Lyntm1.1Calo, LYN proto-oncogene, Src family tyrosine kinase; targeted mutation 1.1 Clifford A Lowell
Lyntm1Sor, LYN proto-oncogene, Src family tyrosine kinase; targeted mutation 1, Philippe Soriano
Tg(Itgax-cre)1-1Reiz, transgene insertion 1-1, Boris Reizis
Copyright: This image is from Lamagna C, Proc Natl Acad Sci U S A 2013 Aug 27;110(35):E3311-20. Copyright 2013 National Academy of Sciences, U.S.A. J:200745

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory