Phenotype Images associated with this Gene

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Phenotype Images associated with this Gene

Symbol
Name
ID

Nkx2-5
NK2 homeobox 5
MGI:97350

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Click on allele symbol for full phenotype details.

	Caption: General and heart phenotype of Hspb7^tm1.1Chen/Hspb7^tm1.1Chen Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ mice (details) Represented Alleles: Hspb7^tm1.1Chen, heat shock protein family, member 7 (cardiovascular); targeted mutation 1.1, Ju Chen Nkx2-5^tm1(cre)Rjs, NK2 homeobox 5; targeted mutation 1, Robert J Schwartz Copyright: This image is from Wu T, Proc Natl Acad Sci U S A 2017 Nov 7;114(45):11956-11961. Copyright 2017 National Academy of Sciences, U.S.A. J:256653
	Caption: Abnormal heart development and coronary vasculogenesis in Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ Zfpm2^tm1Sho/Zfpm2^tm2Sho mice (details) Represented Alleles: Nkx2-5^tm1(cre)Rjs, NK2 homeobox 5; targeted mutation 1, Robert J Schwartz Zfpm2^tm1Sho, zinc finger protein, multitype 2; targeted mutation 1, Stuart Orkin Zfpm2^tm2Sho, zinc finger protein, multitype 2; targeted mutation 2, Stuart Orkin Copyright: This image is from Zhou B, J Clin Invest 2009 Jun;119(6):1462-76 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:150452
	Caption: Paucity of coronary vessels in Zfpm2^tm1Sho/Zfpm2^tm2Sho Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ hearts (details) Represented Alleles: Nkx2-5^tm1(cre)Rjs, NK2 homeobox 5; targeted mutation 1, Robert J Schwartz Zfpm2^tm1Sho, zinc finger protein, multitype 2; targeted mutation 1, Stuart Orkin Zfpm2^tm2Sho, zinc finger protein, multitype 2; targeted mutation 2, Stuart Orkin Copyright: This image is from Zhou B, J Clin Invest 2009 Jun;119(6):1462-76 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:150452
	Caption: Edema, peripheral hemorrhage, and reduced coronary plexus in Gata4^tm1.1Wtp/Gata4^tm1Sho Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ embryos and enlarged dilated ventricles and increased fibrosis in Gata4^tm1.1Wtp/Gata4^tm1Sho Tg(Myh6-cre)2182Mds/0 hearts (details) Represented Alleles: Gata4^tm1.1Wtp, GATA binding protein 4; targeted mutation 1.1, William T Pu Gata4^tm1Sho, GATA binding protein 4; targeted mutation 1, Stuart Orkin Nkx2-5^tm1(cre)Rjs, NK2 homeobox 5; targeted mutation 1, Robert J Schwartz Tg(Myh6-cre)2182Mds, transgene insertion 2182, Michael D Schneider Copyright: This image is from Zhou B, J Clin Invest 2009 Jun;119(6):1462-76 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:150452

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