Symbol Name ID |
Pdgfrb
platelet derived growth factor receptor, beta polypeptide MGI:97531 |
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Caption: Mutant (E15.5) displays parallel outflow tracts which is diagnosed as double outlet right ventricle and hypoplastic pulmonary by ECM histopathology.
(details)
Represented Alleles:
Pdgfrbb2b2903Clo,
platelet derived growth factor receptor, beta polypeptide; Bench to Bassinet Program (B2B/CVDC), mutation 2903 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: EFIC Summary
(details)
Represented Alleles:
Pdgfrbb2b2903Clo,
platelet derived growth factor receptor, beta polypeptide; Bench to Bassinet Program (B2B/CVDC), mutation 2903 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Serial 2D ECM image stack in the coronal plane of mutant (E15.5) reveals double outlet right ventricle (DORV), atrioventricular septal defect (AVSD), and small pulmonary artery (PA).
Click thumbnail to play movie. (details) Represented Alleles:
Pdgfrbb2b2903Clo,
platelet derived growth factor receptor, beta polypeptide; Bench to Bassinet Program (B2B/CVDC), mutation 2903 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant (E15.5) is runted, has hydrops, petechiae, and micrognathia.
(details)
Represented Alleles:
Pdgfrbb2b2903Clo,
platelet derived growth factor receptor, beta polypeptide; Bench to Bassinet Program (B2B/CVDC), mutation 2903 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant (E15.5) presents with clinodactyly on hindlimb digits.
(details)
Represented Alleles:
Pdgfrbb2b2903Clo,
platelet derived growth factor receptor, beta polypeptide; Bench to Bassinet Program (B2B/CVDC), mutation 2903 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant (E15.5) has an abnormal arrangement of the outflow tracts which is diagnosd as overriding aorta, right aortic arch, and a hypoplastic transverse aorta forming vascular ring by ECM imaging.
(details)
Represented Alleles:
Pdgfrbb2b2903Clo,
platelet derived growth factor receptor, beta polypeptide; Bench to Bassinet Program (B2B/CVDC), mutation 2903 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
|
|
Caption: EFIC Summary
(details)
Represented Alleles:
Pdgfrbb2b2903Clo,
platelet derived growth factor receptor, beta polypeptide; Bench to Bassinet Program (B2B/CVDC), mutation 2903 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Serial 2D ECM image stack in the coronal plane of mutant reveals overriding aorta, atrioventricular septal defect (AVSD), cushion-like AV valve, right aortic arch (RAA) with left patent ductus arteriosis (PDA), hypoplastic transverse aorta forming a vascular ring, aberrant left subclavian artery from left PDA-ascending aorta junction, ventricular non-compaction.
Click thumbnail to play movie. (details) Represented Alleles:
Pdgfrbb2b2903Clo,
platelet derived growth factor receptor, beta polypeptide; Bench to Bassinet Program (B2B/CVDC), mutation 2903 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant (E15.5) exhibits micrognathia, hydrops, and petechiae.
(details)
Represented Alleles:
Pdgfrbb2b2903Clo,
platelet derived growth factor receptor, beta polypeptide; Bench to Bassinet Program (B2B/CVDC), mutation 2903 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/17/2024 MGI 6.24 |
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