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Symbol Name ID |
Pthlh
parathyroid hormone-like peptide MGI:97800 |
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Caption: Pthlhtm2Ack/Pthlhtm2Ack mice show growth retardation, premature aging, osteopenia, kyphosis, muscle atrophy, decrease in adipose tissue, swelling of the brain, and thin skin
(details)
Represented Alleles:
Pthlhtm2Ack,
parathyroid hormone-like peptide; targeted mutation 2, Andrew C Karaplis
Copyright: This image is from Miao D, Proc Natl Acad Sci U S A 2008 Dec 23;105(51):20309-14. Copyright 2008 National Academy of Sciences, U.S.A.
J:142669
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Caption: Skeletal growth retardation caused by impaired growth plate chondrocyte proliferation in Pthlhtm2Ack/Pthlhtm2Ack mice
(details)
Represented Alleles:
Pthlhtm2Ack,
parathyroid hormone-like peptide; targeted mutation 2, Andrew C Karaplis
Copyright: This image is from Miao D, Proc Natl Acad Sci U S A 2008 Dec 23;105(51):20309-14. Copyright 2008 National Academy of Sciences, U.S.A.
J:142669
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Caption: Pthlhtm2Ack/Pthlhtm2Ack mice develop severe premature osteoporosis resulting from defects of osteoblastic bone formation
(details)
Represented Alleles:
Pthlhtm2Ack,
parathyroid hormone-like peptide; targeted mutation 2, Andrew C Karaplis
Copyright: This image is from Miao D, Proc Natl Acad Sci U S A 2008 Dec 23;105(51):20309-14. Copyright 2008 National Academy of Sciences, U.S.A.
J:142669
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Caption: Alizarin red S stained skeletal images of hemizygous and homozygous Tg(Col2a1-PTHR1*H223R)AHju and Pthlhtm1Hmk/Pthlhtm1Hmk mice
(details)
Represented Alleles:
Pthlhtm1Hmk,
parathyroid hormone-like peptide; targeted mutation 1, Henry M Kronenberg
Tg(Col2a1-PTHR1*H223R)AHju,
transgene insertion A, Harald Juppner
Copyright: This image is from Schipani E, Proc Natl Acad Sci U S A 1997 Dec 9;94(25):13689-94. Copyright 1997 National Academy of Sciences, U.S.A.
J:77639
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Caption: Histological tibiae sections of mice homozygous for Tg(Col2a1-PTHR1*H223R)AHju, mice homozygous for Tg(Col2a1-PTHR1*H223R)AHju and Pthlhtm1Hmk and mice homozygous for Pthlhtm1Hmk
(details)
Represented Alleles:
Pthlhtm1Hmk,
parathyroid hormone-like peptide; targeted mutation 1, Henry M Kronenberg
Tg(Col2a1-PTHR1*H223R)AHju,
transgene insertion A, Harald Juppner
Copyright: This image is from Schipani E, Proc Natl Acad Sci U S A 1997 Dec 9;94(25):13689-94. Copyright 1997 National Academy of Sciences, U.S.A.
J:77639
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Caption: Skeletal phenotypes and tibial histology of Pthtm1Dgo/Pthtm1Dgo, Pthlhtm1Hmk/Pthlhtm1Hmk and Pthtm1Dgo/Pthtm1Dgo Pthlhtm1Hmk/Pthlhtm1Hmk mice
(details)
Represented Alleles:
Pthlhtm1Hmk,
parathyroid hormone-like peptide; targeted mutation 1, Henry M Kronenberg
Pthtm1Dgo,
parathyroid hormone; targeted mutation 1, David Goltzman
Copyright: This image is from Miao D, J Clin Invest 2002 May;109(9):1173-82 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright.
J:76407
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Caption: Quantitation of bone parameters of Pthtm1Dgo/Pthtm1Dgo, Pthlhtm1Hmk/Pthlhtm1Hmk and Pthtm1Dgo/Pthtm1Dgo Pthlhtm1Hmk/Pthlhtm1Hmk mice
(details)
Represented Alleles:
Pthlhtm1Hmk,
parathyroid hormone-like peptide; targeted mutation 1, Henry M Kronenberg
Pthtm1Dgo,
parathyroid hormone; targeted mutation 1, David Goltzman
Copyright: This image is from Miao D, J Clin Invest 2002 May;109(9):1173-82 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright.
J:76407
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Caption: Skeletal phenotypes of wild type, Tg(Col2a1-PTHLH)2Ecw/0, Pthlhtm1Hmk/Pthlhtm1Hmk, and Pthlhtm1Hmk/Pthlhtm1Hmk Tg(Col2a1-PTHLH)2Ecw/0 mice
(details)
Represented Alleles:
Pthlhtm1Hmk,
parathyroid hormone-like peptide; targeted mutation 1, Henry M Kronenberg
Tg(Col2a1-PTHLH)2Ecw,
transgene insertion 2, Eleanor C Weir
Copyright: This image is from Philbrick WM, Proc Natl Acad Sci U S A 1998 Sep 29;95(20):11846-51. Copyright 1998 National Academy of Sciences, U.S.A.
J:50144
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Caption: Dental phenotype of Pthlhtm1Hmk/Pthlhtm1Hmk mice rescued with Tg(Col2a1-PTHLH)2Ecw and Tg(KRT14-PTHLH)7Wmp transgenes
(details)
Represented Alleles:
Pthlhtm1Hmk,
parathyroid hormone-like peptide; targeted mutation 1, Henry M Kronenberg
Tg(Col2a1-PTHLH)2Ecw,
transgene insertion 2, Eleanor C Weir
Tg(KRT14-PTHLH)7Wmp,
transgene insertion 7, William M Philbrick
Copyright: This image is from Philbrick WM, Proc Natl Acad Sci U S A 1998 Sep 29;95(20):11846-51. Copyright 1998 National Academy of Sciences, U.S.A.
J:50144
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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