Phenotype Images associated with this Gene

About Help FAQ

Phenotype Images associated with this Gene

Symbol
Name
ID

Sox2
SRY (sex determining region Y)-box 2
MGI:98364

Click on thumbnail to view full size image with links to phenotype annotations.
Click on allele symbol for full phenotype details.

	Caption: Sox2^tm1.2Vlcg/Sox2^tm1.2Vlcg and Sox2^tm1.1Vep/Sox2^tm1.2Vlcg embryos form disorganized extraembryonic tissues, but fail to form the epiblast, phenocopying Sox2^tm1.1Vep/Sox2^tm1.1Vep embryos (details) Represented Alleles: Sox2^tm1.1Vep, SRY (sex determining region Y)-box 2; targeted mutation 1.1, Vasso Episkopou Sox2^tm1.1Vlcg, SRY (sex determining region Y)-box 2; targeted mutation 1.1, Velocigene Sox2^tm1.2Vlcg, SRY (sex determining region Y)-box 2; targeted mutation 1.2, Velocigene Copyright: This image is from Mandalos N, PLoS One 2012;7(9):e45768, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:191980
	Caption: Sox2^tm1.1Lan/Sox2^tm1.1Lan Tg(Scgb1a1-cre)1Kkw/0 mice show cuboidal-to-squamous epithelium lacking goblet, Clara and ciliated cells in the conducting airway epithelium (details) Represented Alleles: Sox2^tm1.1Lan, SRY (sex determining region Y)-box 2; targeted mutation 1.1, Richard A Lang Copyright: This image is from Tompkins DH, PLoS One 2009;4(12):e8248, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:155963
	Caption: Impaired goblet cell differentiation after pulmonary allergen sensitization in Sox2^tm1.1Lan/Sox2^tm1.1Lan Tg(Scgb1a1-cre)1Kkw/0 mice (details) Represented Alleles: Sox2^tm1.1Lan, SRY (sex determining region Y)-box 2; targeted mutation 1.1, Richard A Lang Copyright: This image is from Tompkins DH, PLoS One 2009;4(12):e8248, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:155963
	Caption: Male Sox2^tm1Rlb/Sox2⁺ mice exhibit small testes with sperm blockage in the seminiferous tubules (details) Represented Alleles: Sox2^tm1Rlb, SRY (sex determining region Y)-box 2; targeted mutation 1, Robin Lovell-Badge Copyright: This image is from Kelberman D, J Clin Invest 2006 Sep;116(9):2442-55 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:114458
	Caption: Abnormal morphology of the pituitary in Sox2^tm1Rlb/Sox2⁺ mice (details) Represented Alleles: Sox2^tm1Rlb, SRY (sex determining region Y)-box 2; targeted mutation 1, Robin Lovell-Badge Copyright: This image is from Kelberman D, J Clin Invest 2006 Sep;116(9):2442-55 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:114458

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24