Phenotype Images associated with this Gene

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Phenotype Images associated with this Gene

Symbol
Name
ID

Sox2
SRY (sex determining region Y)-box 2
MGI:98364

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Click on allele symbol for full phenotype details.

	Caption: Sox2^tm1.2Vlcg/Sox2^tm1.2Vlcg and Sox2^tm1.1Vep/Sox2^tm1.2Vlcg embryos form disorganized extraembryonic tissues, but fail to form the epiblast, phenocopying Sox2^tm1.1Vep/Sox2^tm1.1Vep embryos (details) Represented Alleles: Sox2^tm1.1Vep, SRY (sex determining region Y)-box 2; targeted mutation 1.1, Vasso Episkopou Sox2^tm1.1Vlcg, SRY (sex determining region Y)-box 2; targeted mutation 1.1, Velocigene Sox2^tm1.2Vlcg, SRY (sex determining region Y)-box 2; targeted mutation 1.2, Velocigene Copyright: This image is from Mandalos N, PLoS One 2012;7(9):e45768, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:191980
	Caption: Sox2^tm1.1Lan/Sox2^tm1.1Lan Tg(Scgb1a1-cre)1Kkw/0 mice show cuboidal-to-squamous epithelium lacking goblet, Clara and ciliated cells in the conducting airway epithelium (details) Represented Alleles: Sox2^tm1.1Lan, SRY (sex determining region Y)-box 2; targeted mutation 1.1, Richard A Lang Copyright: This image is from Tompkins DH, PLoS One 2009;4(12):e8248, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:155963
	Caption: Impaired goblet cell differentiation after pulmonary allergen sensitization in Sox2^tm1.1Lan/Sox2^tm1.1Lan Tg(Scgb1a1-cre)1Kkw/0 mice (details) Represented Alleles: Sox2^tm1.1Lan, SRY (sex determining region Y)-box 2; targeted mutation 1.1, Richard A Lang Copyright: This image is from Tompkins DH, PLoS One 2009;4(12):e8248, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:155963
	Caption: Male Sox2^tm1Rlb/Sox2⁺ mice exhibit small testes with sperm blockage in the seminiferous tubules (details) Represented Alleles: Sox2^tm1Rlb, SRY (sex determining region Y)-box 2; targeted mutation 1, Robin Lovell-Badge Copyright: This image is from Kelberman D, J Clin Invest 2006 Sep;116(9):2442-55 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:114458
	Caption: Abnormal morphology of the pituitary in Sox2^tm1Rlb/Sox2⁺ mice (details) Represented Alleles: Sox2^tm1Rlb, SRY (sex determining region Y)-box 2; targeted mutation 1, Robin Lovell-Badge Copyright: This image is from Kelberman D, J Clin Invest 2006 Sep;116(9):2442-55 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:114458

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