Phenotype Images associated with this Gene

About Help FAQ

Phenotype Images associated with this Gene

Symbol
Name
ID

Tgfb1
transforming growth factor, beta 1
MGI:98725

Click on thumbnail to view full size image with links to phenotype annotations.
Click on allele symbol for full phenotype details.

	Caption: Reduced size, kyphosis, tooth abnormalities, and decreased mineral density and dental attrition in Tgfb1^{tm1(Tgfb3)Kul}/Tgfb1^{tm1(Tgfb3)Kul} mice (details) Represented Alleles: Tgfb1^{tm1(Tgfb3)Kul}, transforming growth factor, beta 1; targeted mutation 1, Ashok B Kulkarni Copyright: This image is from Hall BE, J Biol Chem 2013 Nov 1;288(44):32074-92 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:204892
	Caption: Defects in secondary ossification in Tgfb1^{tm1(Tgfb3)Kul}/Tgfb1^{tm1(Tgfb3)Kul} mice (details) Represented Alleles: Tgfb1^{tm1(Tgfb3)Kul}, transforming growth factor, beta 1; targeted mutation 1, Ashok B Kulkarni Copyright: This image is from Hall BE, J Biol Chem 2013 Nov 1;288(44):32074-92 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:204892
	Caption: Tgfb1^{tm1(Tgfb3)Kul}/Tgfb1^{tm1(Tgfb3)Kul} mice remain small and thin on a high fat dough diet (details) Represented Alleles: Tgfb1^{tm1(Tgfb3)Kul}, transforming growth factor, beta 1; targeted mutation 1, Ashok B Kulkarni Copyright: This image is from Hall BE, J Biol Chem 2013 Nov 1;288(44):32074-92 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:204892
	Caption: Reduction in adipose tissue underlying the skin dermis, reduced adipocyte size and no development of steatosis in Tgfb1^{tm1(Tgfb3)Kul}/Tgfb1^{tm1(Tgfb3)Kul} mice fed a high fat dough diet (details) Represented Alleles: Tgfb1^{tm1(Tgfb3)Kul}, transforming growth factor, beta 1; targeted mutation 1, Ashok B Kulkarni Copyright: This image is from Hall BE, J Biol Chem 2013 Nov 1;288(44):32074-92 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:204892
	Caption: Lung and salivary gland inflammation in Tgfb1^tm2.1Doe/Tgfb1^tm2.1Doe Tg(Lck-cre)548Jxm/? (b,e) and Tgfb1^tm1Doe/Tgfb1^tm2.1Doe Tg(Lck-cre)548Jxm/? (c,f) mice (details) Represented Alleles: Tgfb1^tm1Doe, transforming growth factor, beta 1; targeted mutation 1, Thomas Doetschman Tgfb1^tm2.1Doe, transforming growth factor, beta 1; targeted mutation 2.1, Thomas Doetschman Tg(Lck-cre)548Jxm, transgene insertion 548, Jamey Marth Copyright: This image is from Azhar M, Genesis 2009 Jun;47(6):423-31, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:150024
	Caption: Tgfb1^tm1Jmu/Tgfb1^tm1Jmu mice develop fatal multiorgan inflammation (details) Represented Alleles: Tgfb1^tm1Jmu, transforming growth factor, beta 1; targeted mutation 1, John Munger Copyright: This image is from Yang Z, J Cell Biol 2007 Mar 12;176(6):787-93, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:120085
	Caption: Abnormal vascular development in Tgfb1^tm1Jmu/Tgfb1^tm1Jmu mice and fewer Langerhans cells in Tgfb1^tm1Jmu/Tgfb1^tm1Jmu and Itgb6^tm1Des/Itgb6^tm1Des mice (details) Represented Alleles: Itgb6^tm1Des, integrin beta 6; targeted mutation 1, Dean Sheppard Tgfb1^tm1Jmu, transforming growth factor, beta 1; targeted mutation 1, John Munger Copyright: This image is from Yang Z, J Cell Biol 2007 Mar 12;176(6):787-93, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:120085
	Caption: Histopathological analysis on lung and heart tissues of Tgfb1^tm1N/Tgfb1^tm1N mice (details) Represented Alleles: Tgfb1^tm1N, transforming growth factor, beta 1; targeted mutation 1, National Institutes of Health Copyright: This image is from Kulkarni AB, Proc Natl Acad Sci U S A 1993 Jan 15;90(2):770-4. Copyright 1993 National Academy of Sciences, U.S.A. J:50848

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24