Phenotype Images associated with this Gene

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Phenotype Images associated with this Gene

Symbol
Name
ID

Tgfb1
transforming growth factor, beta 1
MGI:98725

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Click on allele symbol for full phenotype details.

	Caption: Reduced size, kyphosis, tooth abnormalities, and decreased mineral density and dental attrition in Tgfb1^{tm1(Tgfb3)Kul}/Tgfb1^{tm1(Tgfb3)Kul} mice (details) Represented Alleles: Tgfb1^{tm1(Tgfb3)Kul}, transforming growth factor, beta 1; targeted mutation 1, Ashok B Kulkarni Copyright: This image is from Hall BE, J Biol Chem 2013 Nov 1;288(44):32074-92 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:204892
	Caption: Defects in secondary ossification in Tgfb1^{tm1(Tgfb3)Kul}/Tgfb1^{tm1(Tgfb3)Kul} mice (details) Represented Alleles: Tgfb1^{tm1(Tgfb3)Kul}, transforming growth factor, beta 1; targeted mutation 1, Ashok B Kulkarni Copyright: This image is from Hall BE, J Biol Chem 2013 Nov 1;288(44):32074-92 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:204892
	Caption: Tgfb1^{tm1(Tgfb3)Kul}/Tgfb1^{tm1(Tgfb3)Kul} mice remain small and thin on a high fat dough diet (details) Represented Alleles: Tgfb1^{tm1(Tgfb3)Kul}, transforming growth factor, beta 1; targeted mutation 1, Ashok B Kulkarni Copyright: This image is from Hall BE, J Biol Chem 2013 Nov 1;288(44):32074-92 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:204892
	Caption: Reduction in adipose tissue underlying the skin dermis, reduced adipocyte size and no development of steatosis in Tgfb1^{tm1(Tgfb3)Kul}/Tgfb1^{tm1(Tgfb3)Kul} mice fed a high fat dough diet (details) Represented Alleles: Tgfb1^{tm1(Tgfb3)Kul}, transforming growth factor, beta 1; targeted mutation 1, Ashok B Kulkarni Copyright: This image is from Hall BE, J Biol Chem 2013 Nov 1;288(44):32074-92 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:204892
	Caption: Lung and salivary gland inflammation in Tgfb1^tm2.1Doe/Tgfb1^tm2.1Doe Tg(Lck-cre)548Jxm/? (b,e) and Tgfb1^tm1Doe/Tgfb1^tm2.1Doe Tg(Lck-cre)548Jxm/? (c,f) mice (details) Represented Alleles: Tgfb1^tm1Doe, transforming growth factor, beta 1; targeted mutation 1, Thomas Doetschman Tgfb1^tm2.1Doe, transforming growth factor, beta 1; targeted mutation 2.1, Thomas Doetschman Tg(Lck-cre)548Jxm, transgene insertion 548, Jamey Marth Copyright: This image is from Azhar M, Genesis 2009 Jun;47(6):423-31, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:150024
	Caption: Tgfb1^tm1Jmu/Tgfb1^tm1Jmu mice develop fatal multiorgan inflammation (details) Represented Alleles: Tgfb1^tm1Jmu, transforming growth factor, beta 1; targeted mutation 1, John Munger Copyright: This image is from Yang Z, J Cell Biol 2007 Mar 12;176(6):787-93, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:120085
	Caption: Abnormal vascular development in Tgfb1^tm1Jmu/Tgfb1^tm1Jmu mice and fewer Langerhans cells in Tgfb1^tm1Jmu/Tgfb1^tm1Jmu and Itgb6^tm1Des/Itgb6^tm1Des mice (details) Represented Alleles: Itgb6^tm1Des, integrin beta 6; targeted mutation 1, Dean Sheppard Tgfb1^tm1Jmu, transforming growth factor, beta 1; targeted mutation 1, John Munger Copyright: This image is from Yang Z, J Cell Biol 2007 Mar 12;176(6):787-93, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:120085
	Caption: Histopathological analysis on lung and heart tissues of Tgfb1^tm1N/Tgfb1^tm1N mice (details) Represented Alleles: Tgfb1^tm1N, transforming growth factor, beta 1; targeted mutation 1, National Institutes of Health Copyright: This image is from Kulkarni AB, Proc Natl Acad Sci U S A 1993 Jan 15;90(2):770-4. Copyright 1993 National Academy of Sciences, U.S.A. J:50848

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