Symbol Name ID |
Wnt5a
wingless-type MMTV integration site family, member 5A MGI:98958 |
Caption: Primordial germ cell depletion in Ror2Y324C/Ror2Y324C and Wnt5atm1Amc/Wnt5atm1Amc mice
(details)
Represented Alleles:
Ror2Y324C,
receptor tyrosine kinase-like orphan receptor 2; Tyr324Cys
Wnt5atm1Amc,
wingless-type MMTV integration site family, member 5A; targeted mutation 1, Andrew P McMahon
Copyright: This image is from Laird DJ, PLoS Genet 2011 Dec;7(12):e1002428, and is displayed under the terms of the Creative Commons Attribution 4.0 International License.
J:179805
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Caption: Mutant 3077-006-2 (E15.5) exhibits parallel outflow tracts, pulmonary stenosis, and small left atrium later diagnosed as double outlet right ventricle (DORV), hypoplastic pulmonary artery, and hypoplastic left atrium by ECM histopathology.
(details)
Represented Alleles:
b2b3077Clo,
Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo
Wnt5ab2b3077.1Clo,
wingless-type MMTV integration site family, member 5A; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: EFIC Summary
(details)
Represented Alleles:
b2b3077Clo,
Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo
Wnt5ab2b3077.1Clo,
wingless-type MMTV integration site family, member 5A; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Serial 2D ECM image stack of 3077-006-2 (E15.5) in the coronal plane reveals double outlet right ventricle (DORV), atrioventricular septal defect (AVSD), common atrium, hypoplastic pulmonary artery (PA), hypoplastic left atrium, and ventricular myocardial non-compaction.
Click thumbnail to play movie. (details) Represented Alleles:
b2b3077Clo,
Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo
Wnt5ab2b3077.1Clo,
wingless-type MMTV integration site family, member 5A; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Color flow spectral Doppler imaging of mutant 3077-006-2 (E15.5) in the sagittal view shows only aorta overriding over septum, suggesting double outlet right ventricle (DORV) with pulmonary stenosis (PS) or pulmonary atresia.
(details)
Represented Alleles:
b2b3077Clo,
Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo
Wnt5ab2b3077.1Clo,
wingless-type MMTV integration site family, member 5A; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant 3077-006-2 (E15.5) presents with hydrops, petechiae, short snout, micrognathia, short limbs, syndactyly, clubbed feet, and short tail.
(details)
Represented Alleles:
b2b3077Clo,
Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo
Wnt5ab2b3077.1Clo,
wingless-type MMTV integration site family, member 5A; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant 3077-006-2 (E15.5) shows a cleft lip.
(details)
Represented Alleles:
b2b3077Clo,
Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo
Wnt5ab2b3077.1Clo,
wingless-type MMTV integration site family, member 5A; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant 3077-006-2 (E15.5) presents with a cleft palate.
(details)
Represented Alleles:
b2b3077Clo,
Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo
Wnt5ab2b3077.1Clo,
wingless-type MMTV integration site family, member 5A; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant 3077-006-2 (E15.5) exhibits a short gut.
(details)
Represented Alleles:
b2b3077Clo,
Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo
Wnt5ab2b3077.1Clo,
wingless-type MMTV integration site family, member 5A; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant 3077-006-2 (E15.5) has an abnormal placement of the gonads and abnormal kidneys, later confirmed as duplex kidney with some glomerular cysts by histology
(details)
Represented Alleles:
b2b3077Clo,
Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo
Wnt5ab2b3077.1Clo,
wingless-type MMTV integration site family, member 5A; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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