Symbol Name ID |
Wnt5a
wingless-type MMTV integration site family, member 5A MGI:98958 |
Caption: Mutant 3077-006-2 (E15.5) exhibits duplex kidney with some glomerular cysts.
(details)
Represented Alleles:
b2b3077Clo,
Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo
Wnt5ab2b3077.1Clo,
wingless-type MMTV integration site family, member 5A; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant 3077-006-3 (E15.5) exhibits a large, single outflow which was later diagnosed as persistent truncus arteriosis (PTA) by ECM histopathology.
(details)
Represented Alleles:
b2b3077Clo,
Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo
Wnt5ab2b3077.1Clo,
wingless-type MMTV integration site family, member 5A; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: EFIC Summary
(details)
Represented Alleles:
b2b3077Clo,
Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo
Wnt5ab2b3077.1Clo,
wingless-type MMTV integration site family, member 5A; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Serial 2D image stack of 3077-006-3 (E15.5) in the coronal plane reveals persistent truncus arteriosis (PTA) (Type 1).
Click thumbnail to play movie. (details) Represented Alleles:
b2b3077Clo,
Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo
Wnt5ab2b3077.1Clo,
wingless-type MMTV integration site family, member 5A; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Color flow spectral doppler imaging of 3077-006-3 (E15.5) in the sagittal view shows only one great artery originating from the heart indicating persistent truncus arteriosis (PTA).
Click thumbnail to play movie. (details) Represented Alleles:
b2b3077Clo,
Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo
Wnt5ab2b3077.1Clo,
wingless-type MMTV integration site family, member 5A; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption:
(details)
Represented Alleles:
b2b3077Clo,
Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo
Wnt5ab2b3077.1Clo,
wingless-type MMTV integration site family, member 5A; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant 3077-006-3 (E15.5) shows hydrops, petechiae, short snout, micrognathia, short limbs, clubbed feet, syndactuly, and short tail.
(details)
Represented Alleles:
b2b3077Clo,
Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo
Wnt5ab2b3077.1Clo,
wingless-type MMTV integration site family, member 5A; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant 3077-006-3 (E15.5) exhibits a short gut.
(details)
Represented Alleles:
b2b3077Clo,
Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo
Wnt5ab2b3077.1Clo,
wingless-type MMTV integration site family, member 5A; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant 3077-006-3 (E15.5) only has a right thymus gland which is extremely hypoplastic.
(details)
Represented Alleles:
b2b3077Clo,
Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo
Wnt5ab2b3077.1Clo,
wingless-type MMTV integration site family, member 5A; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant 3077-006-1 (E15.5) shows a small left ventricle and a single outflow tract, later diagnosed as persistent truncus arteriosis (PTA) type 1 by ECM histopathology.
(details)
Represented Alleles:
b2b3077Clo,
Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo
Wnt5ab2b3077.1Clo,
wingless-type MMTV integration site family, member 5A; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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