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Symbol Name ID |
Ptpn11
protein tyrosine phosphatase, non-receptor type 11 MGI:99511 |
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Caption: Embryonic lethality in Ptpn11tm1Ckq/Ptpn11+ Hprt1tm1(CAG-cre)Mnn/Hprt1+ mice
(details)
Represented Alleles:
Hprt1tm1(CAG-cre)Mnn,
hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, Jeffrey R Mann
Ptpn11tm1Ckq,
protein tyrosine phosphatase, non-receptor type 11; targeted mutation 1, Cheng-Kui Qu
Copyright: This image is from Xu D, J Exp Med 2011 Sep 26;208(10):1977-88, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License.
J:177285
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Caption: Increased spleen weight in Ptpn11tm1Ckq/Ptpn11+ Tg(Mx1-cre)1Cgn/0 mice
(details)
Represented Alleles:
Ptpn11tm1Ckq,
protein tyrosine phosphatase, non-receptor type 11; targeted mutation 1, Cheng-Kui Qu
Tg(Mx1-cre)1Cgn,
transgene insertion 1, University of Cologne
Copyright: This image is from Xu D, J Exp Med 2011 Sep 26;208(10):1977-88, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License.
J:177285
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Caption: Ptpn11tm4.2Bgn/Ptpn11+ mice demonstrate phenotypic abnormalities similar to those in human Leopard syndrome (LS)
(details)
Represented Alleles:
Ptpn11tm4.2Bgn,
protein tyrosine phosphatase, non-receptor type 11; targeted mutation 4.2, Benjamin G Neel
Copyright: This image is from Marin TM, J Clin Invest 2011 Mar 1;121(3):1026-43 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright.
J:172033
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Caption: Ptpn11tm4.2Bgn/Ptpn11+ mice have pathological cardiac hypertrophy
(details)
Represented Alleles:
Ptpn11tm4.2Bgn,
protein tyrosine phosphatase, non-receptor type 11; targeted mutation 4.2, Benjamin G Neel
Copyright: This image is from Marin TM, J Clin Invest 2011 Mar 1;121(3):1026-43 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright.
J:172033
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Caption: Myofiber disarray, enlarged nuclei, and fibrosis in 52-week-old Ptpn11tm4.2Bgn/Ptpn11+ hearts
(details)
Represented Alleles:
Ptpn11tm4.2Bgn,
protein tyrosine phosphatase, non-receptor type 11; targeted mutation 4.2, Benjamin G Neel
Copyright: This image is from Marin TM, J Clin Invest 2011 Mar 1;121(3):1026-43 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright.
J:172033
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Caption: Ptpn11tm4.2Bgn/Ptpn11+ mice have hypertrophic cardiomyopathy that progresses to chamber dilation
(details)
Represented Alleles:
Ptpn11tm4.2Bgn,
protein tyrosine phosphatase, non-receptor type 11; targeted mutation 4.2, Benjamin G Neel
Copyright: This image is from Marin TM, J Clin Invest 2011 Mar 1;121(3):1026-43 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright.
J:172033
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Caption: Defects in the skin, lung and intestine of Egfrwa2/Egfrwa2 Ptpn11tm1Paw/+ mice
(details)
Represented Alleles:
Egfrwa2,
epidermal growth factor receptor; waved 2
Ptpn11tm1Paw,
protein tyrosine phosphatase, non-receptor type 11; targeted mutation 1, Anthony Pawson
Copyright: This image is from Qu CK, Proc Natl Acad Sci U S A 1999 Jul 20;96(15):8528-33. Copyright 1999 National Academy of Sciences, U.S.A.
J:75413
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/17/2024 MGI 6.24 |
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