Phenotype Images associated with this Gene

About Help FAQ

Phenotype Images associated with this Gene

Symbol
Name
ID

S1pr2
sphingosine-1-phosphate receptor 2
MGI:99569

Click on thumbnail to view full size image with links to phenotype annotations.
Click on allele symbol for full phenotype details.

	Caption: Absence of spiral ganglion neurons in inner ears of S1pr2^tm1Rlp/S1pr2^tm1Rlp S1pr3^tm1Rlp/S1pr3^tm1Rlp and S1pr2^tm1Rlp/S1pr2^tm1Rlp mice (details) Represented Alleles: S1pr2^tm1Rlp, sphingosine-1-phosphate receptor 2; targeted mutation 1, Richard L Proia S1pr3^tm1Rlp, sphingosine-1-phosphate receptor 3; targeted mutation 1, Richard L Proia Copyright: This image is from Kono M, J Biol Chem 2007 Apr;282(14):10690-6 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:121165
	Caption: Inner ear abnormalities in S1pr2^tm1Rlp/S1pr2^tm1Rlp mice (details) Represented Alleles: S1pr2^tm1Rlp, sphingosine-1-phosphate receptor 2; targeted mutation 1, Richard L Proia Copyright: This image is from Kono M, J Biol Chem 2007 Apr;282(14):10690-6 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:121165
	Caption: Increased pigmentation in stria vascularis and degeneration of the organ of Corti in S1pr2^tm1Rlp/S1pr2^tm1Rlp mice (details) Represented Alleles: S1pr2^tm1Rlp, sphingosine-1-phosphate receptor 2; targeted mutation 1, Richard L Proia Copyright: This image is from Kono M, J Biol Chem 2007 Apr;282(14):10690-6 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:121165
	Caption: Bleeding phenotypes of mice carrying different combinations of deleted S1p receptors (details) Represented Alleles: S1pr1^tm1Rlp, sphingosine-1-phosphate receptor 1; targeted mutation 1, Richard L Proia S1pr2^tm1Rlp, sphingosine-1-phosphate receptor 2; targeted mutation 1, Richard L Proia S1pr3^tm1Rlp, sphingosine-1-phosphate receptor 3; targeted mutation 1, Richard L Proia Copyright: This image is from Kono M, J Biol Chem 2004 Jul 9;279(28):29367-73 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:106055
	Caption: Immature vascular network in S1pr1^tm1Rlp/S1pr1^tm1Rlp S1pr2^tm1Rlp/S1pr2^tm1Rlp and S1pr1^tm1Rlp/S1pr1^tm1Rlp S1pr2^tm1Rlp/S1pr2^tm1Rlp S1pr3^tm1Rlp/S1pr3^tm1Rlp embryos (details) Represented Alleles: S1pr1^tm1Rlp, sphingosine-1-phosphate receptor 1; targeted mutation 1, Richard L Proia S1pr2^tm1Rlp, sphingosine-1-phosphate receptor 2; targeted mutation 1, Richard L Proia S1pr3^tm1Rlp, sphingosine-1-phosphate receptor 3; targeted mutation 1, Richard L Proia Copyright: This image is from Kono M, J Biol Chem 2004 Jul 9;279(28):29367-73 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:106055
	Caption: Hemorrhage in S1pr2^tm1Rlp/S1pr2^tm1Rlp S1pr3^tm1Rlp/S1pr3^tm1Rlp embryos (details) Represented Alleles: S1pr2^tm1Rlp, sphingosine-1-phosphate receptor 2; targeted mutation 1, Richard L Proia S1pr3^tm1Rlp, sphingosine-1-phosphate receptor 3; targeted mutation 1, Richard L Proia Copyright: This image is from Kono M, J Biol Chem 2004 Jul 9;279(28):29367-73 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:106055
	Caption: Subcutaneous edema and thin endothelial cells in S1pr2^tm1Rlp/S1pr2^tm1Rlp S1pr3^tm1Rlp/S1pr3^tm1Rlp embryos (details) Represented Alleles: S1pr2^tm1Rlp, sphingosine-1-phosphate receptor 2; targeted mutation 1, Richard L Proia S1pr3^tm1Rlp, sphingosine-1-phosphate receptor 3; targeted mutation 1, Richard L Proia Copyright: This image is from Kono M, J Biol Chem 2004 Jul 9;279(28):29367-73 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:106055
	Caption: Discontinuous smooth muscle cell coverage around the aorta in S1pr1^tm1Rlp/S1pr1^tm2Rlp Tg(Tek-cre)1Ywa/? mice (details) Represented Alleles: S1pr1^tm2Rlp, sphingosine-1-phosphate receptor 1; targeted mutation 2, Richard L Proia S1pr2^tm1Rlp, sphingosine-1-phosphate receptor 2; targeted mutation 1, Richard L Proia S1pr3^tm1Rlp, sphingosine-1-phosphate receptor 3; targeted mutation 1, Richard L Proia Tg(Tek-cre)1Ywa, transgene insertion 1, Masashi Yanagisawa Copyright: This image is from Kono M, J Biol Chem 2004 Jul 9;279(28):29367-73 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:106055

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24