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Phenotype Images associated with this Gene
Symbol
Name
ID 		Lama1
laminin, alpha 1
MGI:99892


8 phenotype image(s) for Lama1 alleles
Showing image(s) 1 to 8
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Click on allele symbol for full phenotype details.

Caption: Lama1nmf223/Lama1nmf223 mutants exhibit vitreal and retinal abnormalities (details)
Represented Alleles:
Lama1nmf223, laminin, alpha 1; neuroscience mutagenesis facility, 223
Copyright: This image is from Edwards MM, J Biol Chem 2010 Mar 5;285(10):7697-711 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:160722
Caption: Lama1tm1Olf/Lama1tm1Olf Edil3Tg(Sox2-cre)1Amc/0 mice have a similar but more severe retinal phenotype than Lama1nmf223/Lama1nmf223 mice (details)
Represented Alleles:
Edil3Tg(Sox2-cre)1Amc, EGF-like repeats and discoidin I-like domains 3; transgene insertion 1, Andrew P McMahon
Lama1tm1Olf, laminin, alpha 1; targeted mutation 1, Olivier Lefebvre
Copyright: This image is from Edwards MM, J Biol Chem 2010 Mar 5;285(10):7697-711 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:160722
Caption: Peripheral retinal degeneration is observed in Lama1tm1Olf/Lama1tm1Olf Edil3Tg(Sox2-cre)1Amc/0 mice as early as 4 weeks of age (details)
Represented Alleles:
Edil3Tg(Sox2-cre)1Amc, EGF-like repeats and discoidin I-like domains 3; transgene insertion 1, Andrew P McMahon
Lama1tm1Olf, laminin, alpha 1; targeted mutation 1, Olivier Lefebvre
Copyright: This image is from Edwards MM, J Biol Chem 2010 Mar 5;285(10):7697-711 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:160722
Caption: Lama1nmf223/Lama1tm1.1Olf mice experience vitreal fibroplasia and vessel tortuosity (details)
Represented Alleles:
Lama1nmf223, laminin, alpha 1; neuroscience mutagenesis facility, 223
Lama1tm1.1Olf, laminin, alpha 1; targeted mutation 1.1, Olivier Lefebvre
Copyright: This image is from Edwards MM, J Biol Chem 2010 Mar 5;285(10):7697-711 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:160722
Caption: Primary inner limiting membrane abnormalities are evident in Lama1nmf223/Lama1nmf223 mice (details)
Represented Alleles:
Lama1nmf223, laminin, alpha 1; neuroscience mutagenesis facility, 223
Copyright: This image is from Edwards MM, J Biol Chem 2010 Mar 5;285(10):7697-711 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:160722
Caption: Peripheral inner nuclear layer cell loss is associated with reduced electroretinogram responses in Lama1nmf223/Lama1nmf223 mice (details)
Represented Alleles:
Lama1nmf223, laminin, alpha 1; neuroscience mutagenesis facility, 223
Copyright: This image is from Edwards MM, J Biol Chem 2010 Mar 5;285(10):7697-711 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:160722
Caption: Altered development of astrocytes and blood vessels in Lama1nmf223/Lama1nmf223 retinas (details)
Represented Alleles:
Lama1nmf223, laminin, alpha 1; neuroscience mutagenesis facility, 223
Copyright: This image is from Edwards MM, J Biol Chem 2010 Mar 5;285(10):7697-711 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:160722
Caption: The inner limiting membrane does not form in Lama1tm1Olf/Lama1tm1Olf Edil3Tg(Sox2-cre)1Amc/0 mice (details)
Represented Alleles:
Edil3Tg(Sox2-cre)1Amc, EGF-like repeats and discoidin I-like domains 3; transgene insertion 1, Andrew P McMahon
Lama1tm1Olf, laminin, alpha 1; targeted mutation 1, Olivier Lefebvre
Copyright: This image is from Edwards MM, J Biol Chem 2010 Mar 5;285(10):7697-711 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:160722
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
MGI 6.24 		The Jackson Laboratory