Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  UN
• Reference
  J:39424 Ashman RB, et al., Evidence that two independent host genes influence the severity of tissue damage and susceptibility to acute pyelonephritis in murine systemic candidiasis. Microb Pathog. 1997 Mar;22(3):187-92
• ID
  MGI:1095327

Genes

Gene	Assay Type
Carg2	resistance/susceptibility

Notes

• Experiment
  The strain distribution patterns (SDPs) in 15 AKXL (AKR/J x C57L/J) RI strains suggest that at least two gene families facilitate the tissue damage caused by systemic infection of Candida albicans. One of these genes has been designated as Carg2. The SDPs of this locus, Carg2 does not significantly correlate with any known genetic marker currently mapped in the AKXL set.
  
  The parental strain AKR/J exhibits greater susceptibility to infection by C. albicans compared to parental strain C57L/J.