Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  17
• Reference
  J:41197 Hiai H, et al., To be or not to be a T-lymphomas, that is determined by a dominant gene Tlsm-1 in mouse models. Leukemia. 1997 Apr;11 Suppl 3:193-4
• ID
  MGI:1096484

Genes

Gene	Assay Type
H2	reported elsewhere
lla	visible phenotype

Notes

• Experiment
  SL/Kh is an inbred strains exhibiting high incidence of spontaneous pre-B lymphomas and AKR/JMs is an inbred strain exhibiting high incidence of T-lymphomas. A recessive allele in SL/Kh mice shortened the development of lymphomas and was shown to be dependent on H2 haplotypes. 114 (AKR/JMs x SL/Kh)F2 mice were analyzed for the segregation of the shortened latency phenotype (lla) as a quantitative trait. The results from the F2 cross show that the lla phenotype was significantly associated with H2 class II loci with a maximal LOD score of 7.06.