Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  17
• Reference
  J:39947 Taylor BA, et al., Obesity QTLs on mouse chromosomes 2 and 17. Genomics. 1997 Aug 1;43(3):249-57
• ID
  MGI:1101013

Genes

Gene	Assay Type
Obq4	visible phenotype
D17Mit143	reported elsewhere
D17Mit173	reported elsewhere
D17Mit28	reported elsewhere
D17Mit11	reported elsewhere
D17Mit66	reported elsewhere
D17Mit117	reported elsewhere
D17Mit20	reported elsewhere

Notes

• Experiment
  Statistical analysis of 93 individual genotypes (up to 339 for select markers) from (AKR/J x C57L/J)F2 fat and lean pool mice indicated the presence of a QTL locus on mouse Chromosome 17 affecting the adiposity index. A LOD peak score of 4.6 occurred at a position 5 cM distal to D17Mit143. A broad 1-LOD support interval extended from the centromere to 2 cM distal to D17Mit173. Gene order and percentage of recombination between markers is reported as: D17Mit143 - 5.8 - D17Mit173 - 5.2 - D17Mit28 - 3.4 - D17Mit11 - 3.4 - D17Mit66 - D17Mit117 - 12.3 - D17Mit20. This QTL is reported to account for 6.1% of the phenotypic variance,and is demonstrated to affect males much more than females (LOD = 4.0 vs. LOD = 1.6 respectively.