Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  4
• Reference
  J:45708 Vidal S, et al., Loci predisposing to autoimmunity in MRL-Fas lpr and C57BL/6-Faslpr mice. J Clin Invest. 1998 Feb 1;101(3):696-702
• ID
  MGI:1278420

Genes

Gene	Assay Type
D4Mit12	PCR amplified length variant
Lmb1	visible phenotype
D4Mit33	PCR amplified length variant

Notes

• Experiment
  In a (MRL-Tnfrsf6^lpr x C57BL/6-Tnfrsf6^lpr)F1 cross involving 274 F2 progeny a quantitative trait locus, Lmb1, identifying lymphadenopathy and/or splenomegaly was significantly associated with a region of mouse Chromosome 4 flanked by markers D4Mit12 and D4Mit33. The highest LOD scores were associated with D4Mit12.