Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  10
• Reference
  J:45708 Vidal S, et al., Loci predisposing to autoimmunity in MRL-Fas lpr and C57BL/6-Faslpr mice. J Clin Invest. 1998 Feb 1;101(3):696-702
• ID
  MGI:1278423

Genes

Gene	Assay Type
D10Mit20	PCR amplified length variant
Lmb4	visible phenotype
D10Mit11	PCR amplified length variant

Notes

• Experiment
  In a (MRL-Tnfrsf6^lpr x C57BL/6-Tnfrsf6^lpr)F1 cross involving 274 F2 progeny a quantitative trait locus, Lmb4, identifying lymphadenopathy and/or splenomegaly was significantly associated with a region of mouse Chromosome 10 flanked by markers D10Mit20 and D10Mit11. The highest LOD scores were associated with D10Mit11.