Mapping Data

Experiment

• Experiment
  TEXT-Congenic
• Chromosome
  10
• Reference
  J:15048 Bureau JF, et al., Mapping loci influencing the persistence of Theiler's virus in the murine central nervous system. Nat Genet. 1993 Sep;5(1):87-91
• ID
  MGI:1306954

Genes

Gene	Assay Type
D10Mit14	PCR amplified length variant
Ifng	PCR amplified length variant
Mdm1	PCR amplified length variant
Tmevp2	resistance/susceptibility

Notes

• Experiment
  SJL mice are highly susceptible to TMEV (Theiler's Murine Encephalomyelitis Virus) whereas the congenic strain B10.S is resistant, therefore a (SJL/J x B10.S)F1 x B10.S backcross was established to map loci that control viral persistence. In 79 backcross mice a significant association of a viral persistence locus, Tmevp2 with mouse Chromosome 10 loci D10Mit14, Ifng, and Mdm1 was indicated.