Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  7
• Reference
  J:49054 Butterfield RJ, et al., New genetic loci that control susceptibility and symptoms of experimental allergic encephalomyelitis in inbred mice. J Immunol. 1998 Aug 15;161(4):1860-7
• ID
  MGI:1309750

Genes

Gene	Assay Type
D7Mit85	PCR amplified length variant
Eae43	visible phenotype
D7Mit39	PCR amplified length variant

Notes

• Experiment
  Authors isolated quantitative trait loci believed to be invloved with the disease frequency of experimental allergic encephalomyelitis (EAE). (SJL/J x B10.S/DvTe)F2; SJL/J (susceptible) and B10.S/DvTe (resistant) mice; were bred to create F2 progeny used in the analysis.
  
  A genome wide scan of 291 affected and 390 unaffected animals indicated the presence of a locus mapping to mouse Chromosome 7 between D7Mit185 and D7Mit39, named Eae4 by the authors.
  
  6.30.2015 Curator Note: Because Eae4 was originally mapped in J:29171 in 1995 using (ABH x NOD)F1 x NOD backcross mice; which differs from the cross used here; we consider the current study a separate mapping experiment and have named this QTL Eae43.