Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  4
• Reference
  J:49558 Santos J, et al., A new candidate site for a tumor suppressor gene involved in mouse thymic lymphomagenesis is located on the distal part of chromosome 4. Oncogene. 1998 Aug 20;17(7):925-9
• ID
  MGI:1313326

Genes

Gene	Assay Type
Tlsr10	visible phenotype
D4Mit205b	PCR amplified length variant
D4Mit203	PCR amplified length variant
Tlsr3	visible phenotype
D4Mit68	PCR amplified length variant

Notes

• Experiment
  Primary thymic lymphomas induced by gamma rays in (C57BL/6J x BALB/cJ)F1 mice and (BALB/cJ x C57BL/6J)F1 mice were examined for allelic loss using a number of mouse Chromosome 4 markers. The Tlsr2 tumor suppressor region mapping was centered at D4Mit205b.
  
  10.20.2015_djr Curator Note: Because Tlsr2 was originally mapped in J:31797 in 1996 using
  (C57BL/6J x RF/J)F1 mice, which differ from the population used here, we consider the current study a separate mapping experiment and have named this QTL Tlsr10.
  
  A new critical region/quantitative trait locus involved in thymic lymphomagenesis, Tlsr3, was placed between D4Mit203 and D4Mit68.