Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  17
• Reference
  J:50945 Schmutte C, et al., Refined chromosomal localization of the mismatch repair and hereditary nonpolyposis colorectal cancer genes hMSH2 and hMSH6. Cancer Res. 1998 Nov 15;58(22):5023-6
• ID
  MGI:1315016

Genes

Gene	Assay Type	Description
Eif2ak2
Sos1
Msh6	Southern analysis	Msh6 cDNA2
Msh2
Lhcgr

Notes

• Experiment
  Offspring types indicate alleles inherited from F1 parent.
  

CROSS

• Type
  Backcross, female
• Female Parent
  <b> <b> <b> <b> <b>/<s> <s> <s> <s> <s>
• Strain
  (C57BL/6J x M. spretus)F1
• Male Parent
  <b> <b> <b> <b> <b>/<b> <b> <b> <b> <b>
• Strain
  C57BL/6J
• Mapping Panel
  Copeland-Jenkins
• Allele 1
  b from C57BL/6J
• Allele 2
  s from M. spretus

CROSS Data

MC #mice	Eif2ak2	Sos1	Msh6	Msh2	Lhcgr
66	b	b	b	b	b
86	s	s	s	s	s
0	s	b	b	b	b
0	b	s	s	s	s
1	s	s	b	b	b
1	b	b	s	s	s
0	s	s	s	b	b
0	b	b	b	s	s
0	s	s	s	s	b
1	b	b	b	b	s

Additional Mice Typed Only for Specific Pairs of Loci

Marker 1	Marker 2	# Recombinants	# Parentals
Eif2ak2	Sos1	1	6
Sos1	Msh6	1	2
Msh6	Msh2	0	34
Msh2	Lhcgr	0	36

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Eif2ak2	Sos1	1	162	0.617	0.615
Sos1	Msh6	3	158	1.899	1.086
Msh6	Msh2	0	189	0.000	0.000
Msh2	Lhcgr	1	191	0.524	0.522