Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  17
• Reference
  J:48777 Redkar AA, et al., High-resolution mapping of sperm function defects in the t complex fourth inversion. Mamm Genome. 1998 Oct;9(10):825-30
• ID
  MGI:1330579

Genes

Gene	Assay Type
D17Leh54
Hba-ps4
Pim1
D17Shp1
Ccua	visible phenotype
Stop1-p	visible phenotype
Ccub	visible phenotype
Cryaa
Stop1-d	visible phenotype
D17Leh89
Hst6
In(17)4t

Notes

• Reference
  The authors in J:107013 (Hui L; Lu J; Han Y; Pilder SH) in 2006 show that the original Ccub can be divided into two separate genetic elements one (Ccub1) mapping between Dnahc8 and D17Mit191 and the other (Ccub2) mapping with Pou5f1. Tsga2 was suggested as a strong candidate for Ccub1
• Experiment
  The authors used mice carrying a series of M. spretus-M.m. domesticus recombinant Chromosome 17 homologs and a complete t haplotype strain (M. spretus - +/t to map elements of the Hst6 region within the In(17)4t complex inversion. Two loci responsible for a "curlicue" sperm flagellar curvature phenotype, Ccua and Ccub, were mapped within the Hst6 region. Stop1-p and Stop1-d, acutely affecting the ability of sperm to penetrate the oolemma, were also identified in the In(17)4t region. The order of loci mapped on mouse Chromosome 17 was reported as: D17Leh54 - Hba-ps4 - Pim1 - D17Shp1 - Ccua - Stop-1p - Ccub - Cryaa - Stop-d - D17Leh89.